Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1962269..1962414 Replicon chromosome
Accession NZ_CP056530
Organism Klebsiella pneumoniae strain RHBSTW-00433

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1962305..1962407 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1962269..1962414 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV193_RS09600 1957399..1959459 + 2061 WP_004151449.1 oligopeptidase B -
HV193_RS09605 1959463..1960122 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV193_RS09610 1960201..1960431 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV193_RS09615 1960544..1960918 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV193_RS09620 1960922..1961791 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
HV193_RS09625 1961808..1962146 + 339 WP_048982383.1 YebY family protein -
- 1962269..1962414 - 146 - - Antitoxin
- 1962305..1962407 + 103 - - Toxin
HV193_RS09630 1962783..1962926 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV193_RS09635 1963031..1963999 - 969 WP_004151446.1 VirK/YbjX family protein -
HV193_RS09640 1964156..1964809 + 654 WP_060415692.1 protein-serine/threonine phosphatase -
HV193_RS09645 1964806..1964997 - 192 WP_002911395.1 YebW family protein -
HV193_RS09650 1965095..1965334 - 240 WP_002911393.1 YebV family protein -
HV193_RS09655 1965450..1966883 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163620 NZ_CP056530:1962305-1962407 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163620 NZ_CP056530:c1962414-1962269 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References