163559

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 807829..808483 Replicon chromosome
Accession NZ_CP056473
Organism Citrobacter freundii strain RHBSTW-00477

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HV211_RS03935 Protein ID WP_096755799.1
Coordinates 808076..808483 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HV211_RS03930 Protein ID WP_096755798.1
Coordinates 807829..808095 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV211_RS03905 803037..804476 - 1440 WP_181631883.1 6-phospho-beta-glucosidase BglA -
HV211_RS03910 804597..805325 - 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
HV211_RS03915 805378..805689 + 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
HV211_RS03920 805853..806512 + 660 WP_096755796.1 hemolysin III family protein -
HV211_RS03925 806592..807572 - 981 WP_115257540.1 tRNA-modifying protein YgfZ -
HV211_RS03930 807829..808095 + 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
HV211_RS03935 808076..808483 + 408 WP_096755799.1 protein YgfX Toxin
HV211_RS03940 808529..809050 - 522 WP_096755800.1 flavodoxin FldB -
HV211_RS03945 809163..810059 + 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
HV211_RS03950 810083..810796 + 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HV211_RS03955 810802..812535 + 1734 WP_181631884.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T163559 WP_096755799.1 NZ_CP056473:808076-808483 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

>T163559 NZ_CP072686:c827044-826667 [Escherichia coli]
ATGAAAACATTACCTGACACACACGTACGGGAGGCATCGTGCTGCCCGTCTCCCGTCACCATCTGGCATACACTGCTCAC
CCGACTGCTGGACCAGCATTACGGCCTCACACTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACCGAACAGTAAATAACATTACTCTGGGTAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT163559 WP_096755798.1 NZ_CP056473:807829-808095 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT163559 NZ_CP072686:c827465-827091 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGGCCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATATGGCTGTTTATCCGACACTGGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References