Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1848388..1848533 Replicon chromosome
Accession NZ_CP056432
Organism Klebsiella pneumoniae strain RHBSTW-00510

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1848424..1848526 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1848388..1848533 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV225_RS09075 1843518..1845578 + 2061 WP_004151449.1 oligopeptidase B -
HV225_RS09080 1845582..1846241 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV225_RS09085 1846320..1846550 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV225_RS09090 1846663..1847037 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV225_RS09095 1847041..1847910 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
HV225_RS09100 1847927..1848265 + 339 WP_009307539.1 YebY family protein -
- 1848388..1848533 - 146 - - Antitoxin
- 1848424..1848526 + 103 - - Toxin
HV225_RS09105 1848902..1849045 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV225_RS09110 1849150..1850118 - 969 WP_004151446.1 VirK/YbjX family protein -
HV225_RS09115 1850275..1850928 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
HV225_RS09120 1850925..1851116 - 192 WP_002911395.1 YebW family protein -
HV225_RS09125 1851214..1851453 - 240 WP_002911393.1 YebV family protein -
HV225_RS09130 1851569..1853002 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163481 NZ_CP056432:1848424-1848526 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163481 NZ_CP056432:c1848533-1848388 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References