Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1879967..1880112 Replicon chromosome
Accession NZ_CP056425
Organism Klebsiella pneumoniae strain RHBSTW-00515

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1880003..1880105 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1879967..1880112 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV227_RS09175 1875097..1877157 + 2061 WP_181486760.1 oligopeptidase B -
HV227_RS09180 1877161..1877820 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV227_RS09185 1877899..1878129 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV227_RS09190 1878242..1878616 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV227_RS09195 1878620..1879489 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HV227_RS09200 1879506..1879844 + 339 WP_002911404.1 YebY family protein -
- 1879967..1880112 - 146 - - Antitoxin
- 1880003..1880105 + 103 - - Toxin
HV227_RS09205 1880481..1880624 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV227_RS09210 1880729..1881697 - 969 WP_004151446.1 VirK/YbjX family protein -
HV227_RS09215 1881854..1882507 + 654 WP_064165395.1 protein-serine/threonine phosphatase -
HV227_RS09220 1882504..1882695 - 192 WP_002911395.1 YebW family protein -
HV227_RS09225 1882793..1883032 - 240 WP_002911393.1 YebV family protein -
HV227_RS09230 1883148..1884581 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163461 NZ_CP056425:1880003-1880105 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163461 NZ_CP056425:c1880112-1879967 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References