Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1828152..1828297 Replicon chromosome
Accession NZ_CP056372
Organism Klebsiella pneumoniae strain RHBSTW-00636

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1828188..1828290 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1828152..1828297 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV253_RS08930 1823282..1825342 + 2061 WP_004151449.1 oligopeptidase B -
HV253_RS08935 1825346..1826005 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV253_RS08940 1826084..1826314 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV253_RS08945 1826427..1826801 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV253_RS08950 1826805..1827674 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
HV253_RS08955 1827691..1828029 + 339 WP_016529031.1 YebY family protein -
- 1828152..1828297 - 146 - - Antitoxin
- 1828188..1828290 + 103 - - Toxin
HV253_RS08960 1828665..1828808 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV253_RS08965 1828913..1829881 - 969 WP_004151446.1 VirK/YbjX family protein -
HV253_RS08970 1830038..1830691 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
HV253_RS08975 1830688..1830879 - 192 WP_002911395.1 YebW family protein -
HV253_RS08980 1830977..1831216 - 240 WP_002911393.1 YebV family protein -
HV253_RS08985 1831332..1832765 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163330 NZ_CP056372:1828188-1828290 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163330 NZ_CP056372:c1828297-1828152 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References