Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2030099..2030240 Replicon chromosome
Accession NZ_CP056314
Organism Citrobacter freundii strain RHBSTW-00830

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2030134..2030237 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2030099..2030240 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV290_RS09555 2026546..2027208 - 663 WP_003833802.1 exodeoxyribonuclease X -
HV290_RS09560 2027232..2027888 - 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
HV290_RS09565 2027995..2028225 - 231 WP_003034925.1 DNA polymerase III subunit theta -
HV290_RS09570 2028369..2028743 + 375 WP_086529333.1 CopC domain-containing protein YobA -
HV290_RS09575 2028747..2029619 + 873 WP_086529332.1 copper homeostasis membrane protein CopD -
HV290_RS09580 2029640..2029978 + 339 WP_003034934.1 YebY family protein -
- 2030099..2030240 - 142 - - Antitoxin
- 2030134..2030237 + 104 - - Toxin
HV290_RS09585 2030370..2031449 - 1080 WP_136397057.1 phage integrase Arm DNA-binding domain-containing protein -
HV290_RS09590 2031427..2031687 - 261 WP_072211989.1 hypothetical protein -
HV290_RS09595 2031751..2034222 - 2472 WP_148373976.1 exonuclease -
HV290_RS09600 2034364..2034690 - 327 WP_181523356.1 Rrf2 family transcriptional regulator -
HV290_RS09605 2034748..2034984 - 237 WP_181523363.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage aac(6')-If - 2022895..2105545 82650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163275 NZ_CP056314:2030134-2030237 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT163275 NZ_CP056314:c2030240-2030099 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References