Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1975888..1976032 Replicon chromosome
Accession NZ_CP056307
Organism Klebsiella pneumoniae strain RHBSTW-00832

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1975924..1976026 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1975888..1976032 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV292_RS09725 1971018..1973078 + 2061 WP_004151449.1 oligopeptidase B -
HV292_RS09730 1973082..1973741 - 660 WP_021440386.1 exodeoxyribonuclease X -
HV292_RS09735 1973820..1974050 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV292_RS09740 1974163..1974537 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV292_RS09745 1974541..1975410 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HV292_RS09750 1975427..1975765 + 339 WP_002911404.1 YebY family protein -
- 1975888..1976032 - 145 - - Antitoxin
- 1975924..1976026 + 103 - - Toxin
HV292_RS09755 1976159..1976518 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
HV292_RS09760 1976517..1976996 + 480 WP_064147222.1 lysis protein -
HV292_RS09765 1977785..1977976 + 192 WP_064147221.1 hypothetical protein -
HV292_RS09770 1977927..1979291 + 1365 WP_181247924.1 hypothetical protein -
HV292_RS09775 1979541..1979969 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
HV292_RS09780 1979979..1980260 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163252 NZ_CP056307:1975924-1976026 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT163252 NZ_CP056307:c1976032-1975888 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References