Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1894655..1894800 Replicon chromosome
Accession NZ_CP056301
Organism Klebsiella pneumoniae strain RHBSTW-00843

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1894691..1894793 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1894655..1894800 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV294_RS09165 1889785..1891845 + 2061 WP_004151449.1 oligopeptidase B -
HV294_RS09170 1891849..1892508 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV294_RS09175 1892587..1892817 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV294_RS09180 1892930..1893304 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV294_RS09185 1893308..1894177 + 870 WP_040230666.1 copper homeostasis membrane protein CopD -
HV294_RS09190 1894194..1894532 + 339 WP_016529031.1 YebY family protein -
- 1894655..1894800 - 146 - - Antitoxin
- 1894691..1894793 + 103 - - Toxin
HV294_RS09195 1895168..1895311 - 144 WP_040230665.1 Ecr family regulatory small membrane protein -
HV294_RS09200 1895416..1896384 - 969 WP_014907334.1 VirK/YbjX family protein -
HV294_RS09205 1896541..1897194 + 654 WP_016529030.1 protein-serine/threonine phosphatase -
HV294_RS09210 1897191..1897382 - 192 WP_002911395.1 YebW family protein -
HV294_RS09215 1897480..1897719 - 240 WP_002911393.1 YebV family protein -
HV294_RS09220 1897835..1899268 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163232 NZ_CP056301:1894691-1894793 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163232 NZ_CP056301:c1894800-1894655 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References