Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867565..1867710 Replicon chromosome
Accession NZ_CP056275
Organism Klebsiella pneumoniae strain RHBSTW-00867

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1867601..1867703 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867565..1867710 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV307_RS09030 1862695..1864755 + 2061 WP_004151449.1 oligopeptidase B -
HV307_RS09035 1864759..1865418 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV307_RS09040 1865497..1865727 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV307_RS09045 1865840..1866214 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV307_RS09050 1866218..1867087 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HV307_RS09055 1867104..1867442 + 339 WP_002911404.1 YebY family protein -
- 1867565..1867710 - 146 - - Antitoxin
- 1867601..1867703 + 103 - - Toxin
HV307_RS09060 1868078..1868221 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV307_RS09065 1868326..1869294 - 969 WP_074195444.1 DUF535 family protein -
HV307_RS09070 1869451..1870104 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HV307_RS09075 1870101..1870292 - 192 WP_002911395.1 YebW family protein -
HV307_RS09080 1870390..1870629 - 240 WP_002911393.1 YebV family protein -
HV307_RS09085 1870745..1872178 - 1434 WP_181475345.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T163193 NZ_CP056275:1867601-1867703 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT163193 NZ_CP056275:c1867710-1867565 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References