Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2032914..2033052 Replicon chromosome
Accession NZ_CP056260
Organism Klebsiella aerogenes strain RHBSTW-00898

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2032949..2033052 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2032914..2033052 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV316_RS09680 2028023..2030083 + 2061 WP_032705952.1 oligopeptidase B -
HV316_RS09685 2030086..2030745 - 660 WP_015366006.1 exodeoxyribonuclease X -
HV316_RS09690 2030825..2031055 - 231 WP_015366007.1 DNA polymerase III subunit theta -
HV316_RS09695 2031190..2031564 + 375 WP_015366008.1 CopC domain-containing protein YobA -
HV316_RS09700 2031568..2032437 + 870 WP_032705951.1 copper homeostasis membrane protein CopD -
HV316_RS09705 2032451..2032792 + 342 WP_015366010.1 YebY family protein -
- 2032914..2033052 - 139 - - Antitoxin
- 2032949..2033052 + 104 - - Toxin
HV316_RS09710 2033184..2034263 - 1080 WP_032708609.1 phage integrase Arm DNA-binding domain-containing protein -
HV316_RS09715 2034238..2034510 - 273 WP_071609883.1 excisionase -
HV316_RS09720 2034577..2034969 - 393 WP_125961766.1 hypothetical protein -
HV316_RS09725 2034999..2035502 - 504 WP_032716233.1 siphovirus Gp157 family protein -
HV316_RS09730 2035499..2037835 - 2337 WP_032716232.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2028023..2088575 60552


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163171 NZ_CP056260:2032949-2033052 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 139 bp

>AT163171 NZ_CP056260:c2033052-2032914 [Klebsiella aerogenes]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References