Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 4674399..4674918 Replicon chromosome
Accession NZ_CP056251
Organism Citrobacter sp. RHBSTW-00903

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HV320_RS23120 Protein ID WP_019078244.1
Coordinates 4674399..4674680 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HV320_RS23125 Protein ID WP_103283421.1
Coordinates 4674670..4674918 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV320_RS23105 4671400..4671864 + 465 WP_016151476.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
HV320_RS23110 4671886..4672407 - 522 WP_049270665.1 hypothetical protein -
HV320_RS23115 4672407..4674371 - 1965 WP_103283422.1 type VI secretion system tip protein VgrG -
HV320_RS23120 4674399..4674680 - 282 WP_019078244.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HV320_RS23125 4674670..4674918 - 249 WP_103283421.1 plasmid stabilization protein Antitoxin
HV320_RS23130 4675213..4675686 - 474 WP_016155556.1 hypothetical protein -
HV320_RS23135 4675729..4678230 - 2502 WP_103283420.1 type VI secretion system ATPase TssH -
HV320_RS23140 4678221..4679168 - 948 WP_103284439.1 type VI secretion system baseplate subunit TssG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10988.76 Da        Isoelectric Point: 10.4466

>T163144 WP_019078244.1 NZ_CP056251:c4674680-4674399 [Citrobacter sp. RHBSTW-00903]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

>T163144 NZ_CP072408:791182-791592 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9073.37 Da        Isoelectric Point: 4.5680

>AT163144 WP_103283421.1 NZ_CP056251:c4674918-4674670 [Citrobacter sp. RHBSTW-00903]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELVEDAELNRIADEREDGKRIKVSLN
DL

Download         Length: 249 bp

>AT163144 NZ_CP072408:790935-791201 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References