Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2155577..2155718 Replicon chromosome
Accession NZ_CP056245
Organism Citrobacter freundii strain RHBSTW-00915

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2155612..2155715 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2155577..2155718 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV325_RS10540 2152024..2152686 - 663 WP_003833802.1 exodeoxyribonuclease X -
HV325_RS10545 2152710..2153366 - 657 WP_046671220.1 carbon-nitrogen hydrolase family protein -
HV325_RS10550 2153473..2153703 - 231 WP_003034925.1 DNA polymerase III subunit theta -
HV325_RS10555 2153847..2154221 + 375 WP_044711069.1 CopC domain-containing protein YobA -
HV325_RS10560 2154225..2155097 + 873 WP_032935389.1 copper homeostasis membrane protein CopD -
HV325_RS10565 2155118..2155456 + 339 WP_003034934.1 YebY family protein -
- 2155577..2155718 - 142 - - Antitoxin
- 2155612..2155715 + 104 - - Toxin
HV325_RS10570 2155848..2156927 - 1080 WP_049016043.1 phage integrase Arm DNA-binding domain-containing protein -
HV325_RS10575 2156905..2157165 - 261 WP_049016044.1 hypothetical protein -
HV325_RS10580 2157452..2159299 - 1848 WP_049016093.1 hypothetical protein -
HV325_RS10585 2159633..2159818 - 186 WP_049016045.1 hypothetical protein -
HV325_RS10590 2159811..2160005 - 195 WP_049025790.1 hypothetical protein -
HV325_RS10595 2160373..2160636 + 264 WP_071891820.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2086924..2216141 129217


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163112 NZ_CP056245:2155612-2155715 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT163112 NZ_CP056245:c2155718-2155577 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References