163105

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4403421..4403956 Replicon chromosome
Accession NZ_CP056244
Organism Citrobacter freundii strain RHBSTW-00923

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HV327_RS20885 Protein ID WP_181517643.1
Coordinates 4403669..4403956 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HV327_RS20880 Protein ID WP_137399198.1
Coordinates 4403421..4403672 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV327_RS20850 4398434..4399282 + 849 WP_135912711.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ -
HV327_RS20855 4399279..4400037 + 759 WP_115259672.1 phosphonate C-P lyase system protein PhnK -
HV327_RS20860 4400145..4400825 + 681 WP_117343579.1 phosphonate C-P lyase system protein PhnL -
HV327_RS20865 4400822..4401958 + 1137 WP_181517641.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
HV327_RS20870 4401961..4402506 + 546 WP_096758664.1 ribose 1,5-bisphosphokinase -
HV327_RS20875 4402579..4403337 + 759 WP_181517642.1 phosphonate metabolism protein PhnP -
HV327_RS20880 4403421..4403672 + 252 WP_137399198.1 antitoxin Antitoxin
HV327_RS20885 4403669..4403956 + 288 WP_181517643.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HV327_RS20890 4403953..4404282 - 330 WP_096758667.1 hypothetical protein -
HV327_RS20895 4404351..4406615 - 2265 WP_181490715.1 hybrid sensor histidine kinase/response regulator -
HV327_RS20900 4406730..4408253 + 1524 WP_181517644.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11172.08 Da        Isoelectric Point: 10.5077

>T163105 WP_181517643.1 NZ_CP056244:4403669-4403956 [Citrobacter freundii]
MSYTVKFREDALKEWQKLDKTIQQQFAKKLKKCGENPHVPSAKLRGIKDCYKIQLRTSRFRLVYQVIDDTLVIAVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

>T163105 NZ_CP072385:618008-618259 [Arachnia propionica]
GTGTCCATCAGCGCCAGCGAGGCCCGCAGGACGTTGTTCCCGCTCATCGAGCAGGTCAACGACGATCGCACTGCCGTCGA
GATCGTTTCCCGCAAGGGGAACGCCGTTCTCATGTCCGCCGATGAATACGCCGCGTGGCAGGAGACGGCCTACCTGTTCC
GTTCCCCCGCCAATGCCCGAAGGCTGCTCGACGCCTACGAGAGGGCCCGGGAAGGACGGAGCGAGGAACACGATCTCATC
CGGGAGGACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.56 Da        Isoelectric Point: 4.2965

>AT163105 WP_137399198.1 NZ_CP056244:4403421-4403672 [Citrobacter freundii]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERNQQPLVDVDLD
SYL

Download         Length: 252 bp

>AT163105 NZ_CP072385:618261-618515 [Arachnia propionica]
GTGCGCCTGGCGTGGGATCCCTCGGCCTGGGAGGATTACACGTACTGGCAGGCCGCGGATAGCCGGATTCTCAAGCGGAT
CAACGCGCTCATCGACACCTGCCTCCGCGATCCCTTCGGTGGGATCGGGAAACCTGAACAACTCAGGTATGGGGCAACGG
GGGCTTGGTCGCGGCGCATCACGGAGGAGCACCGGCTCGTGTATCTCGTCGACGGCGACGACCTGGTGATCCTCCAGGCC
CGGTACCACTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References