Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1950183..1950416 Replicon chromosome
Accession NZ_CP056244
Organism Citrobacter freundii strain RHBSTW-00923

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1950309..1950412 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1950183..1950416 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV327_RS09065 1946729..1947391 - 663 WP_096756686.1 exodeoxyribonuclease X -
HV327_RS09070 1947415..1948071 - 657 WP_153879980.1 carbon-nitrogen hydrolase family protein -
HV327_RS09075 1948178..1948402 - 225 WP_096756688.1 DNA polymerase III subunit theta -
HV327_RS09080 1948547..1948921 + 375 WP_115258189.1 CopC domain-containing protein YobA -
HV327_RS09085 1948926..1949798 + 873 WP_115258190.1 copper homeostasis membrane protein CopD -
HV327_RS09090 1949815..1950153 + 339 WP_181518176.1 YebY family protein -
- 1950183..1950416 - 234 - - Antitoxin
- 1950309..1950412 + 104 - - Toxin
HV327_RS09095 1950490..1951227 - 738 Protein_1778 tyrosine-type recombinase/integrase -
HV327_RS09100 1951229..1951804 + 576 Protein_1779 antiterminator -
HV327_RS09105 1951985..1952482 - 498 WP_135911947.1 hypothetical protein -
HV327_RS09110 1952916..1953194 + 279 WP_016150496.1 hypothetical protein -
HV327_RS09115 1953166..1953714 + 549 WP_060683645.1 lysozyme -
HV327_RS09120 1953711..1954229 + 519 WP_181518177.1 DUF2514 domain-containing protein -
HV327_RS09125 1954316..1954771 + 456 WP_021571192.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1944648..1977166 32518


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163095 NZ_CP056244:1950309-1950412 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 234 bp

>AT163095 NZ_CP056244:c1950416-1950183 [Citrobacter freundii]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGTCCGCGACCAAAGTGGCC
TGAAAAAAAGGACGATTGTCACCCGCTAGAATGCAAAAACCGCAAGTTCTGCAGCCAGAACGTTGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References