Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2994363..2994503 Replicon chromosome
Accession NZ_CP056238
Organism Citrobacter freundii strain RHBSTW-00935

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2994365..2994468 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2994363..2994503 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV330_RS14630 2989602..2989835 - 234 Protein_2876 RusA family crossover junction endodeoxyribonuclease -
HV330_RS14635 2989838..2990038 - 201 WP_057108923.1 hypothetical protein -
HV330_RS14640 2990044..2990631 - 588 WP_181501844.1 DUF1367 family protein -
HV330_RS14645 2990655..2991607 + 953 Protein_2879 IS3 family transposase -
HV330_RS14650 2991819..2992889 + 1071 WP_001180631.1 IS110 family transposase -
HV330_RS14655 2992897..2993112 + 216 Protein_2881 transposase -
HV330_RS14660 2993202..2994287 + 1086 WP_181501845.1 phage integrase Arm DNA-binding domain-containing protein -
- 2994363..2994503 + 141 - - Antitoxin
- 2994365..2994468 - 104 - - Toxin
HV330_RS14665 2994624..2994962 - 339 WP_003034934.1 YebY family protein -
HV330_RS14670 2994983..2995855 - 873 WP_032935389.1 copper homeostasis membrane protein CopD -
HV330_RS14675 2995859..2996233 - 375 WP_181501846.1 CopC domain-containing protein YobA -
HV330_RS14680 2996377..2996607 + 231 WP_003034925.1 DNA polymerase III subunit theta -
HV330_RS14685 2996714..2997370 + 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
HV330_RS14690 2997394..2998056 + 663 WP_003833802.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163076 NZ_CP056238:c2994468-2994365 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT163076 NZ_CP056238:2994363-2994503 [Citrobacter freundii]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References