Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 800272..800926 Replicon chromosome
Accession NZ_CP056229
Organism Citrobacter freundii strain RHBSTW-00968

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HV337_RS04000 Protein ID WP_096755799.1
Coordinates 800519..800926 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HV337_RS03995 Protein ID WP_096755798.1
Coordinates 800272..800538 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV337_RS03970 795486..796919 - 1434 WP_115257538.1 6-phospho-beta-glucosidase BglA -
HV337_RS03975 797040..797768 - 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
HV337_RS03980 797821..798132 + 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
HV337_RS03985 798296..798955 + 660 WP_096755796.1 hemolysin III family protein -
HV337_RS03990 799035..800015 - 981 WP_181490982.1 tRNA-modifying protein YgfZ -
HV337_RS03995 800272..800538 + 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
HV337_RS04000 800519..800926 + 408 WP_096755799.1 protein YgfX Toxin
HV337_RS04005 800972..801493 - 522 WP_096755800.1 flavodoxin FldB -
HV337_RS04010 801606..802502 + 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
HV337_RS04015 802526..803239 + 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HV337_RS04020 803245..804978 + 1734 WP_181490983.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T163033 WP_096755799.1 NZ_CP056229:800519-800926 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

>T163033 NZ_CP072290:461604-461993 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCATTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AATTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCACTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAGTAATTGATTATCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT163033 WP_096755798.1 NZ_CP056229:800272-800538 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT163033 NZ_CP072290:461340-461597 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References