Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3840243..3840900 Replicon chromosome
Accession NZ_CP056199
Organism Enterobacter sp. RHBSTW-00994

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HV346_RS18335 Protein ID WP_181620671.1
Coordinates 3840243..3840653 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HV346_RS18340 Protein ID WP_181620672.1
Coordinates 3840634..3840900 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV346_RS18315 3836236..3837969 - 1734 WP_181620667.1 single-stranded-DNA-specific exonuclease RecJ -
HV346_RS18320 3837975..3838688 - 714 WP_181620668.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HV346_RS18325 3838717..3839613 - 897 WP_181620669.1 site-specific tyrosine recombinase XerD -
HV346_RS18330 3839714..3840235 + 522 WP_181620670.1 flavodoxin FldB -
HV346_RS18335 3840243..3840653 - 411 WP_181620671.1 protein YgfX Toxin
HV346_RS18340 3840634..3840900 - 267 WP_181620672.1 FAD assembly factor SdhE Antitoxin
HV346_RS18345 3841206..3842186 + 981 WP_181620673.1 tRNA-modifying protein YgfZ -
HV346_RS18350 3842250..3842909 - 660 WP_181620674.1 hemolysin III family protein -
HV346_RS18355 3843075..3843386 - 312 WP_181620675.1 N(4)-acetylcytidine aminohydrolase -
HV346_RS18360 3843439..3844170 + 732 WP_181623827.1 MurR/RpiR family transcriptional regulator -
HV346_RS18365 3844287..3845720 + 1434 WP_181620676.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16128.05 Da        Isoelectric Point: 11.7617

>T162968 WP_181620671.1 NZ_CP056199:c3840653-3840243 [Enterobacter sp. RHBSTW-00994]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLVDSRLRWQGK
EWELIGTPWMLNSGMMLRLRKAGGGRRQHLWLAADSMDAQEWRDLRRMMLQLPTQE

Download         Length: 411 bp

>T162968 NZ_CP072203:c2213754-2213473 [Gordonia polyisoprenivorans]
GTGATCCAGTCGTTCGCCACCAAGGACACAGAAAGGGTGTGGGCACGAAAGTTCGTACCCCGCCTCGGACCCGAGCTCAC
TCGGGTGGCGCACCGTAAGTTACAAGCCCTCGACGCCGCCCAGCGACTCGCGGACCTCGCATCCCCTCCCGGCAACAGAC
TCGAACCACTGTCCGGCGACCGCGCCGGACAACACAGCATCCGCGTCAACGACCAGTACCGATTGTGCTTCACCTGGACA
CCGGTTGGACCCGTCGACGTGGAGATCGTCGACTACCACTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10565.06 Da        Isoelectric Point: 5.1340

>AT162968 WP_181620672.1 NZ_CP056199:c3840900-3840634 [Enterobacter sp. RHBSTW-00994]
MDINNKPRIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLEADDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT162968 NZ_CP072203:c2213457-2213173 [Gordonia polyisoprenivorans]
ATGCCCGACTTCGAACCGATCCATCCCGGCGAGACACTCGCCGCCGACTACCTACCCGACTACGGCCTCTCTCAGCGCAA
GCTGGCCGAGCTGATCCACGTCCCTCCGCGCCGCATCAACGAGATCATCCACGGCCGTCGCGCAATAACCCCCGATACCT
CCATTCGACTCGGACGTCTCTTCGGGCAGTCCGAGACCTTCTGGCTGAACATGCAAACTCGTTACGACCTCGAGATCGCC
CGCGCGACAACCGATGTCTCAGACATCACGCCTCTGGCAAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References