Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 56319..56999 Replicon chromosome
Accession NZ_CP056185
Organism Citrobacter sp. RHBSTW-01013

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag HV350_RS00290 Protein ID WP_181629560.1
Coordinates 56319..56660 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag HV350_RS00295 Protein ID WP_181629561.1
Coordinates 56682..56999 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV350_RS00255 51640..51972 - 333 WP_040231546.1 DUF1493 family protein -
HV350_RS00260 51966..52409 - 444 WP_049042695.1 hypothetical protein -
HV350_RS00265 52420..52905 - 486 WP_040231549.1 type VI secretion system tube protein Hcp -
HV350_RS00270 53149..53439 - 291 WP_049042830.1 SymE family type I addiction module toxin -
HV350_RS00275 53566..53757 + 192 WP_049042829.1 toxin-antitoxin system HicB family antitoxin -
HV350_RS00280 53795..55003 + 1209 WP_181629557.1 DUF3644 domain-containing protein -
HV350_RS00285 55372..56205 - 834 WP_181629558.1 DUF4942 domain-containing protein -
HV350_RS00290 56319..56660 - 342 WP_181629560.1 TA system toxin CbtA family protein Toxin
HV350_RS00295 56682..56999 - 318 WP_181629561.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HV350_RS00300 57018..57239 - 222 WP_000691995.1 DUF987 domain-containing protein -
HV350_RS00305 57248..57724 - 477 WP_181629562.1 RadC family protein -
HV350_RS00310 57740..58198 - 459 WP_181629564.1 antirestriction protein -
HV350_RS00315 58301..58540 - 240 WP_181629565.1 DUF905 domain-containing protein -
HV350_RS00320 58633..61791 - 3159 WP_181630609.1 AIDA repeat-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12821.83 Da        Isoelectric Point: 9.7153

>T162909 WP_181629560.1 NZ_CP056185:c56660-56319 [Citrobacter sp. RHBSTW-01013]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDVTVIQEHINAGITLADAVNFLVEKYELVRIDRRSF
NCQEQSPYIRAVDILRARQATGLLRQSRNNAVR

Download         Length: 342 bp

>T162909 NZ_CP072163:1422412-1423674 [Rhizobium sp. B21/90]
ATGACGGTAAGGGTCCTTAACGTCTGGTGGAATGGTCGCATTGTCGGACAGTTCACCCAAGATCAGCACGGCGACATTGG
CTTCGCCTACGCCGAAGCTTGGCTTGAGGACGAAAAGGCACTTCCGCTTTCTGTCTCCCTACCGAAGCGTCCAGAGCGTT
TCTCTCGCCGTGAATGCCGCCCATTTTTTGGCGGCCTACTGCCAGAGGAAAGCCAGCGTCTGGTTGCGGCGCAGGCGTTG
GGTGTTTCACCTGCCAACGACTTCGCCCTTCTTGATCGCTTGGGCGGCGACGTCGCCGGCGCGCTTCAACTTTTGCCCGA
AGACCAGGAACCGATTGGAGGGGGCCTGATTGCCGATCGGCAAACAGCAGCTCTCGATGAGGTCGGAATCGTCCGGATAC
TGGACGCACTTCCGACGAGGCCGCTCTTGGCCGGCCAGGAAGGCTTGAGGCTATCGCTTGCGGGCGCCCAATCAAAAGCT
CCAGTTGTTCTCATCGATGGCCAAGTCGCACTTCCCTTACCAGGCCAGGCGACGACGCACATCTTGAAGCCACCGATTGC
GCGCTTTCCAGGGACGACTGAGAATGAAGCCTTCGCGATGAGGCTTGCTGCCGCAATCGGGCTCGACGTTGCTCCCGTCG
ACCCGAGGTCCGCGAATGGTCGCCCTTTCCTTTTGGTCAACAGATACGATCGCCACCACGATGGCGACGGTGTGGTTCTC
CGCATCCATCAGGAAGACTTCTGCCAAGCGCTGGGTGTGCCACCTGAAACAAAGTATGCAAGCGAGGGGGGGCCGACCTT
CAAGGATTGCTTCGAGCTGTTGCGTCGGGTCTCTGCGCGGCCGGGCACGGACATCGCTAAGCTTTTGGACGCTGCGATTT
TCAATCTCGTCATCGGAAATGCGGATGCTCACGGTAAGAATTTCTCGATCCTCTATGACCATTCTGGACCTAGGATGGCT
CCGCTGTACGACCTGCTTTCCACCGTGGCCTATCCAGATCTTTCCCCTAAATTGGCTATGCGGATCGGCAAACGCGCGAC
GCTTGCTGACATGGACGCTGATGGCTGGCAGGCTTTCTCGAAGGAGACAGGTGTCAGCTTACCTTTAGTGCGCCGTCGGG
TGAAAGAACTGACTGATGCCACAGGGGACGCGATCCCCCGGTTATTGGAAGATATGTCCCCACTTGCCGCAGACCCTGTG
TCGTTAAATCGCGTAGCGGCTTTGATCGCAGACCGTGCCAAACTCGTGGCCCTGAGCATTTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11778.43 Da        Isoelectric Point: 6.9457

>AT162909 WP_181629561.1 NZ_CP056185:c56999-56682 [Citrobacter sp. RHBSTW-01013]
MSNITWGLQRDITPRLGARLLQEGNRLHYLADRASITGKFSEAECLKLNVVFPHFISQMESMVTTGELSPQHAHCVTLYH
NGFTCEADTLGSCGYVYIAVYPTQR

Download         Length: 318 bp

>AT162909 NZ_CP072163:1422185-1422415 [Rhizobium sp. B21/90]
ATGGCAAAACAAGTTAGCAGTCCAGCCGAGATCGGCGCCCTGATCCGCAGCACACGCAAGGCGCAAAACTTGCGGCAGGA
CGAGCTTGCTGGCGTTTCTGGCGTCGGCCTGCGGTTTATCGTCGATCTCGAAGCCGGCAAACCGACAGCACAGATCGGAA
AGGTCTTGCAGGTTTTACAAACGCTCGGTTGTTCGATTGATATTCTAGCCCCAGGTGAACGTAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References