Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4261922..4262640 Replicon chromosome
Accession NZ_CP056180
Organism Citrobacter sp. RHBSTW-01044

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag HV352_RS20455 Protein ID WP_181635032.1
Coordinates 4261922..4262242 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HV352_RS20460 Protein ID WP_181635033.1
Coordinates 4262284..4262640 (-) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV352_RS20425 4257943..4258305 + 363 WP_047358401.1 endoribonuclease SymE -
HV352_RS20430 4258368..4258853 - 486 WP_016151545.1 type VI secretion system tube protein Hcp -
HV352_RS20435 4258872..4259198 - 327 WP_181635030.1 DUF1493 family protein -
HV352_RS20440 4259192..4259641 - 450 WP_003830103.1 hypothetical protein -
HV352_RS20445 4259900..4260772 + 873 WP_103283443.1 HNH endonuclease -
HV352_RS20450 4260972..4261808 - 837 WP_181635031.1 DUF4942 domain-containing protein -
HV352_RS20455 4261922..4262242 - 321 WP_181635032.1 TA system toxin CbtA family protein Toxin
HV352_RS20460 4262284..4262640 - 357 WP_181635033.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HV352_RS20465 4262672..4262893 - 222 WP_181635034.1 DUF987 family protein -
HV352_RS20470 4262902..4263372 - 471 WP_181635035.1 DNA repair protein RadC -
HV352_RS20475 4263442..4264263 - 822 WP_181635036.1 DUF945 domain-containing protein -
HV352_RS20480 4264336..4264785 - 450 WP_181635037.1 hypothetical protein -
HV352_RS20485 4265028..4265831 - 804 WP_181635038.1 hypothetical protein -
HV352_RS20490 4265851..4266285 - 435 WP_181635039.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4259192..4289322 30130


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-105)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12016.77 Da        Isoelectric Point: 6.3175

>T162904 WP_181635032.1 NZ_CP056180:c4262242-4261922 [Citrobacter sp. RHBSTW-01044]
MHISTVPVTVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDTPFHDDSAIQEHIEAGITLADAVNFLVERYELIRTDCKGF
TWQGQTPFLTAINILRARRATGLMNI

Download         Length: 321 bp

>T162904 NZ_CP072162:c3180130-3179846 [Rhizobium sp. B21/90]
ATGGTAATTCTTTCGTTCAAGGATGGGTCGACGCGCGCCGTTGCTTCCGGCGTTGTGCCGAAAGGCTTTCCCGCCGACCT
TGCGCGACGTGCTATTCGCAAGCTGACCATGATCGAATATGCCAACCAGCTTTCGGACCTACGTTCGCCGCCCGCAAATC
ATCTCGAGGCGTTGAAGGGAGATCGTGCCGGCCAGCATTCCATCCGCATCAACGATCAATGGCGGATTTGCTTCGTCTGG
ACCGATGCTGGCGTCGAAGATGTCGAAATTGTCGATTACCACTGA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 12980.50 Da        Isoelectric Point: 5.0484

>AT162904 WP_181635033.1 NZ_CP056180:c4262640-4262284 [Citrobacter sp. RHBSTW-01044]
MQSTTISGTSAEDTSCLQWGLKRNITPCFGARLVQEGNRLYFLADRAGFNGSFSDEEALSLDQAFPLIMKQLERMLTTGE
LDPRSQHSVALHHNGLTSEADTLGSHGYVYIAIYPSQP

Download         Length: 357 bp

>AT162904 NZ_CP072162:c3179835-3179539 [Rhizobium sp. B21/90]
ATGAAGCACATTCTCCCACCGGTGCATCCGGGTGAAATCCTTCGGGAGGAGTATCTGGCACCGCTTAAAATGAGCGCCGG
TGCCCTCGCGCGCAAGCTGAACGTCCCGCGAACGCGCATCGAGCGTCTGGTCGCCGAGGAAACGCCGGTGACCATCGATA
CCGCGTTGCGGTTGGCCCGCTTTTTCGACACGACGCCGGAGTTTTGGATGAATATGCAAACTGGCTACGAACTGAAGCGC
CAGGCGGAGGAAAAGAGAGCCGAGATCGCCGCTATCCCAGTCCTCCATGTCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References