Detailed information of TA system TA162787

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yjhX-yjhQ/YjhX(toxin)
• Location: 4942034..4942853
• Replicon: chromosome
• Accession: NZ_CP056150
• Organism: Klebsiella grimontii strain RHBSTW-00853

Toxin (Protein)

• Gene name: yjhX
• Uniprot ID: A0A9E1D5M6
• Locus tag: HV299_RS23910
• Protein ID: WP_004132607.1
• Coordinates: 4942596..4942853 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yjhQ
• Uniprot ID: A0A9E1DGJ5
• Locus tag: HV299_RS23905
• Protein ID: WP_004132606.1
• Coordinates: 4942034..4942585 (-)
• Length: 184 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HV299_RS23890	4937237..4937791	-	555	WP_154916139.1	type 1 fimbrial protein	-
HV299_RS23895	4940167..4940289	-	123	Protein_4705	VapC toxin family PIN domain ribonuclease	-
HV299_RS23900	4940388..4942016	-	1629	WP_154957001.1	SAM-dependent methyltransferase	-
HV299_RS23905	4942034..4942585	-	552	WP_004132606.1	N-acetyltransferase	Antitoxin
HV299_RS23910	4942596..4942853	-	258	WP_004132607.1	YjhX family toxin	Toxin
HV299_RS23915	4943437..4944621	+	1185	WP_049085652.1	mannonate dehydratase	-
HV299_RS23920	4944698..4946173	+	1476	WP_049130810.1	fructuronate reductase	-
HV299_RS23925	4946310..4947086	+	777	WP_004129229.1	Uxu operon transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Putative toxin of bacterial toxin-antitoxin pair (1-85)

Antitoxin

• GNAT domain (34-121)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 9538.04 Da
• Isoelectric Point: 11.1381

>T162787 WP_004132607.1 NZ_CP056150:c4942853-4942596 [Klebsiella grimontii]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Nucleotide

• Length: 258 bp

>T162787 NZ_CP072110:119063-119353 [Psychrosphaera ytuae]
ATGAAGTTTCATTTATCTAAAAAAGTTCATTCAGATTTAATGAAAATAGGTCGTTACACGCAACTTAACTGGGGCCAAGA
GCAGAGAAATAACTATTTAAAGTTACTGGATAGCGCATTTCATCAAATTGCAGAGAAACCAGAACTAGGTTATGTCTGCG
ATTACATCAGAGAAGGTTATAGAAAGCGGCCTCAAGGCAGCCATGTCATTTATTACAAAGTTTTTGGAAAGGAAGAGGTC
GTAATTATTCGAGTTCTCCATAAAAGCATGGATGTAAAGCGAGCCCTCTAA

Antitoxin

Protein

• Length: 184 a.a.
• Molecular weight: 19990.89 Da
• Isoelectric Point: 7.2343

>AT162787 WP_004132606.1 NZ_CP056150:c4942585-4942034 [Klebsiella grimontii]
MTNHSFTFHVASEGDTNDILHVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGKAVGHILFTRATFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGGLIRHGIEQLKAMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEALKACWMLQPLSS
QPLGRTGQIQCARALMKPEHWRE

Nucleotide

• Length: 552 bp

>AT162787 NZ_CP072110:118822-119061 [Psychrosphaera ytuae]
ATGGCGAAAAATACAAGTGTTACATTAGGTGAGCATTTTGACTCATTTATTAGCCAGCAGTTAGAGTCTGGCAGGTATGG
TTCTGCAAGTGAAGTGATAAGAGCTGGGTTACGAGCCTTAGAAGATCAGGAATTAAAAATGAATAATCTAAGGAACATGT
TAATTGAGGGAGAGAACAGTGGCGTCGCTGATTATTCATATGATTCTCTCTTAAATGATTTGGATAAAGAAAATCATTAA