Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 1058432..1059052 | Replicon | chromosome |
Accession | NZ_CP056148 | ||
Organism | Enterobacter roggenkampii strain RHBSTW-00872 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | A0A1H8SI38 |
Locus tag | HV308_RS05120 | Protein ID | WP_008499287.1 |
Coordinates | 1058432..1058650 (-) | Length | 73 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | V3PBI9 |
Locus tag | HV308_RS05125 | Protein ID | WP_008499288.1 |
Coordinates | 1058678..1059052 (-) | Length | 125 a.a. |
Genomic Context
Location: 1054445..1054705 (261 bp)
Type: Others
Protein ID: WP_006176933.1
Type: Others
Protein ID: WP_006176933.1
Location: 1054708..1054848 (141 bp)
Type: Others
Protein ID: WP_003859006.1
Type: Others
Protein ID: WP_003859006.1
Location: 1055657..1057117 (1461 bp)
Type: Others
Protein ID: WP_059359545.1
Type: Others
Protein ID: WP_059359545.1
Location: 1059365..1059769 (405 bp)
Type: Others
Protein ID: WP_003031976.1
Type: Others
Protein ID: WP_003031976.1
Location: 1059766..1060113 (348 bp)
Type: Others
Protein ID: WP_000612626.1
Type: Others
Protein ID: WP_000612626.1
Location: 1060162..1061700 (1539 bp)
Type: Others
Protein ID: WP_048213845.1
Type: Others
Protein ID: WP_048213845.1
Location: 1054845..1055555 (711 bp)
Type: Others
Protein ID: WP_059359547.1
Type: Others
Protein ID: WP_059359547.1
Location: 1057089..1057556 (468 bp)
Type: Others
Protein ID: WP_008499285.1
Type: Others
Protein ID: WP_008499285.1
Location: 1057674..1058225 (552 bp)
Type: Others
Protein ID: WP_008499286.1
Type: Others
Protein ID: WP_008499286.1
Location: 1058432..1058650 (219 bp)
Type: Toxin
Protein ID: WP_008499287.1
Type: Toxin
Protein ID: WP_008499287.1
Location: 1058678..1059052 (375 bp)
Type: Antitoxin
Protein ID: WP_008499288.1
Type: Antitoxin
Protein ID: WP_008499288.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HV308_RS05090 | 1054445..1054705 | + | 261 | WP_006176933.1 | type B 50S ribosomal protein L31 | - |
HV308_RS05095 | 1054708..1054848 | + | 141 | WP_003859006.1 | type B 50S ribosomal protein L36 | - |
HV308_RS05100 | 1054845..1055555 | - | 711 | WP_059359547.1 | GNAT family N-acetyltransferase | - |
HV308_RS05105 | 1055657..1057117 | + | 1461 | WP_059359545.1 | PLP-dependent aminotransferase family protein | - |
HV308_RS05110 | 1057089..1057556 | - | 468 | WP_008499285.1 | membrane protein | - |
HV308_RS05115 | 1057674..1058225 | - | 552 | WP_008499286.1 | maltose O-acetyltransferase | - |
HV308_RS05120 | 1058432..1058650 | - | 219 | WP_008499287.1 | hemolysin expression modulator Hha | Toxin |
HV308_RS05125 | 1058678..1059052 | - | 375 | WP_008499288.1 | Hha toxicity modulator TomB | Antitoxin |
HV308_RS05130 | 1059365..1059769 | + | 405 | WP_003031976.1 | IS66 family insertion sequence hypothetical protein | - |
HV308_RS05135 | 1059766..1060113 | + | 348 | WP_000612626.1 | IS66 family insertion sequence element accessory protein TnpB | - |
HV308_RS05140 | 1060162..1061700 | + | 1539 | WP_048213845.1 | IS66-like element ISKpn24 family transposase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 73 a.a. Molecular weight: 8612.00 Da Isoelectric Point: 8.9008
>T162759 WP_008499287.1 NZ_CP056148:c1058650-1058432 [Enterobacter roggenkampii]
MSDKPLTKIDYLMRLRRCQSIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFVR
MSDKPLTKIDYLMRLRRCQSIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPTSVWKFVR
Download Length: 219 bp
>T162759 NZ_CP072054:c1302456-1302262 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAAAGATGGAATAAACGAA
CCACTGGAAATAATAATGGAGGTGTTCATGTATAA
Antitoxin
Download Length: 125 a.a. Molecular weight: 14481.28 Da Isoelectric Point: 4.8886
>AT162759 WP_008499288.1 NZ_CP056148:c1059052-1058678 [Enterobacter roggenkampii]
MDEYSPKRHDIAQLKFLCESLYHDCLANLDESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINAQDLQKWRKSGNRLFRCFVNVSRANPVSLSC
MDEYSPKRHDIAQLKFLCESLYHDCLANLDESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINAQDLQKWRKSGNRLFRCFVNVSRANPVSLSC
Download Length: 375 bp
>AT162759 NZ_CP072054:1302085-1302263 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1H8SI38 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | V3PBI9 |