Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1972050..1972194 Replicon chromosome
Accession NZ_CP056145
Organism Klebsiella variicola strain RHBSTW-00883

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1972086..1972188 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1972050..1972194 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV312_RS09500 1967180..1969240 + 2061 WP_012541258.1 oligopeptidase B -
HV312_RS09505 1969244..1969903 - 660 WP_008804267.1 exodeoxyribonuclease X -
HV312_RS09510 1969982..1970212 - 231 WP_012541260.1 DNA polymerase III subunit theta -
HV312_RS09515 1970326..1970700 + 375 WP_012541261.1 CopC domain-containing protein YobA -
HV312_RS09520 1970704..1971573 + 870 WP_117113810.1 copper homeostasis membrane protein CopD -
HV312_RS09525 1971590..1971928 + 339 WP_008804271.1 YebY family protein -
- 1972050..1972194 - 145 - - Antitoxin
- 1972086..1972188 + 103 - - Toxin
HV312_RS09530 1972573..1972716 - 144 WP_142667623.1 Ecr family regulatory small membrane protein -
HV312_RS09535 1972820..1973788 - 969 WP_162493241.1 VirK/YbjX family protein -
HV312_RS09540 1973945..1974598 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
HV312_RS09545 1974595..1974786 - 192 WP_002911395.1 YebW family protein -
HV312_RS09550 1974884..1975123 - 240 WP_002911393.1 YebV family protein -
HV312_RS09555 1975239..1976672 - 1434 WP_080930221.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162743 NZ_CP056145:1972086-1972188 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT162743 NZ_CP056145:c1972194-1972050 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References