Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 506260..506776 Replicon chromosome
Accession NZ_CP056126
Organism Enterobacter asburiae strain RHBSTW-01009

Toxin (Protein)


Gene name relE Uniprot ID A0A8I1FZF0
Locus tag HV349_RS02470 Protein ID WP_054829936.1
Coordinates 506492..506776 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V3EXX3
Locus tag HV349_RS02465 Protein ID WP_008501400.1
Coordinates 506260..506502 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV349_RS02450 502339..503079 + 741 WP_029739262.1 KDGP aldolase family protein -
HV349_RS02455 503116..504252 + 1137 WP_059347252.1 lactonase family protein -
HV349_RS02460 504272..506182 + 1911 WP_059347251.1 BglG family transcription antiterminator -
HV349_RS02465 506260..506502 + 243 WP_008501400.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HV349_RS02470 506492..506776 + 285 WP_054829936.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HV349_RS02475 506780..507244 - 465 WP_048977027.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
HV349_RS02480 507342..509480 - 2139 WP_023310191.1 anaerobic ribonucleoside-triphosphate reductase -
HV349_RS02485 509856..511499 - 1644 WP_059347250.1 alpha,alpha-phosphotrehalase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10908.72 Da        Isoelectric Point: 10.1988

>T162681 WP_054829936.1 NZ_CP056126:506492-506776 [Enterobacter asburiae]
MTYELAFDPRALKEWSKLGETVKDQFKKKLAEVLVNPRVESARLHGLPDCYKIKLRSQGYRLVYQVQDNVVTVFVIAIGK
REKSAVYHDANKRL

Download         Length: 285 bp

>T162681 NZ_CP071954:2854610-2854717 [Escherichia coli]
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACTTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8972.37 Da        Isoelectric Point: 5.0651

>AT162681 WP_008501400.1 NZ_CP056126:506260-506502 [Enterobacter asburiae]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDALIQTVRERLANPQKGIKVSLDDL

Download         Length: 243 bp

>AT162681 NZ_CP071954:c2854560-2854497 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB V3EXX3

References