Detailed information of TA system TA162615

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 5059918..5060459
• Replicon: chromosome
• Accession: NZ_CP056087
• Organism: Pseudomonas argentinensis strain SA190

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SA190iCDA_RS23045
• Protein ID: WP_070886092.1
• Coordinates: 5060163..5060459 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SA190iCDA_RS23040
• Protein ID: WP_070886093.1
• Coordinates: 5059918..5060175 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SA190iCDA_RS23015	5054971..5056002	-	1032	WP_070886097.1	ABC transporter ATP-binding protein	-
SA190iCDA_RS23020	5055999..5056793	-	795	WP_070886096.1	ABC transporter permease subunit	-
SA190iCDA_RS23025	5056790..5057608	-	819	WP_070886203.1	ABC transporter permease	-
SA190iCDA_RS23030	5057661..5058665	-	1005	WP_070886095.1	ABC transporter substrate-binding protein	-
SA190iCDA_RS23035	5058649..5059668	-	1020	WP_070886094.1	substrate-binding domain-containing protein	-
SA190iCDA_RS23040	5059918..5060175	+	258	WP_070886093.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
SA190iCDA_RS23045	5060163..5060459	+	297	WP_070886092.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SA190iCDA_RS23050	5060535..5061854	-	1320	WP_070886091.1	metallopeptidase TldD-related protein	-
SA190iCDA_RS23055	5061854..5063296	-	1443	WP_070886090.1	TldD/PmbA family protein	-
SA190iCDA_RS23060	5063729..5064517	+	789	WP_070886089.1	transporter substrate-binding domain-containing protein	-
SA190iCDA_RS23065	5064535..5065383	-	849	WP_139159489.1	nitrate- and nitrite sensing domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11149.99 Da
• Isoelectric Point: 5.1716

>T162615 WP_070886092.1 NZ_CP056087:5060163-5060459 [Pseudomonas argentinensis]
MAEIVWTDPALEQLDELAHYIALDKPDAARALVSKVVEAVGRLAEFPLSGRVPDELPNSVYREVVVPPCRVFYRPAEGKV
FIIHIMREERVLRAHMLE

Nucleotide

• Length: 297 bp

>T162615 NZ_CP071879:c80002-79748 [Mucilaginibacter rubeus]
ATGGAGATCACAACTTACACTGCCTTCAGGCAGCAACTAAAATCTTTTTTAGATAAGGTGCGGAATGATCATAAGCCTTT
GGTAGTGACAAGTGCCAATGCCGAAGATATTGTTGTGATATCGAAAGCTGATTACGAAAGCATGGAGGAAACTTTCTATC
TTTTAAAAAGCCCTAAAAATGCAGAAAGATTACTTCATGGTATCCAAGAATATGAAAAAGGTTTAGGCAAGGAAAGAAAG
CTACTTGAAGAGTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9642.18 Da
• Isoelectric Point: 6.7259

>AT162615 WP_070886093.1 NZ_CP056087:5059918-5060175 [Pseudomonas argentinensis]
MKVELVTNLKRQATKILADLHESKEPVLITEHGMPSAYLVDVDDYQFMQKRLALLDALAQGERAVVEGNVVSHEQAKERL
GKWLK

Nucleotide

• Length: 258 bp

>AT162615 NZ_CP071879:c79751-79497 [Mucilaginibacter rubeus]
GTGAAGATAATTTTCCAAAACCCTGCATGGGAAGATTACCTTTATTGGCAAACGACAGATAAATCTATTTTAAAGAAGAT
CAACTCTCTTATCAAAGAAATAGAACGAACTCCATATGAAGGAAGTGGAAAGCCCGAACCTTTAAAACATAATTTAGCTG
GTTGGTGGTCGCGCCGGATAAATCTCGAACACAGGCTAATTTACAGAGTAGAAGCAGACGCGATATTTATTCTGCAATGC
AGATATCATTATTGA