Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4142388..4142656 Replicon chromosome
Accession NZ_CP056077
Organism Escherichia coli strain MS1170

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4142516..4142618 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4142388..4142656 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HED12_RS20220 4138942..4139604 - 663 WP_000944256.1 exodeoxyribonuclease X -
HED12_RS20225 4139627..4140283 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
HED12_RS20230 4140385..4140615 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HED12_RS20235 4140754..4141128 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HED12_RS20240 4141132..4142004 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HED12_RS20245 4142017..4142358 + 342 WP_000976472.1 YebY family protein -
- 4142388..4142656 - 269 - - Antitoxin
- 4142516..4142618 + 103 - - Toxin
HED12_RS20250 4142753..4143409 + 657 WP_001357783.1 protein-serine/threonine phosphatase -
HED12_RS20255 4143410..4143601 - 192 WP_001317886.1 YebW family protein -
HED12_RS20260 4143706..4143942 - 237 WP_001295499.1 DUF1480 family protein -
HED12_RS20265 4144060..4145499 - 1440 WP_024190479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162586 NZ_CP056077:4142516-4142618 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTTGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT162586 NZ_CP056077:c4142656-4142388 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCAAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References