Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2031657..2031928 Replicon chromosome
Accession NZ_CP056073
Organism Escherichia coli strain EC50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2031787..2031890 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2031657..2031928 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUS69_RS09650 2028212..2028874 - 663 WP_000944258.1 exodeoxyribonuclease X -
HUS69_RS09655 2028898..2029554 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HUS69_RS09660 2029656..2029886 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUS69_RS09665 2030025..2030399 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUS69_RS09670 2030403..2031275 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
HUS69_RS09675 2031288..2031629 + 342 WP_000976472.1 YebY family protein -
- 2031657..2031928 - 272 - - Antitoxin
- 2031787..2031890 + 104 - - Toxin
HUS69_RS09680 2032025..2032681 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
HUS69_RS09685 2032682..2032873 - 192 WP_001338167.1 YebW family protein -
HUS69_RS09690 2032978..2033214 - 237 WP_001338166.1 YebV family protein -
HUS69_RS09695 2033332..2034771 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T162551 NZ_CP056073:2031787-2031890 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT162551 NZ_CP056073:c2031928-2031657 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References