Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2293327..2293598 Replicon chromosome
Accession NZ_CP056036
Organism Escherichia coli strain EC31

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2293457..2293560 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2293327..2293598 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW39_RS10850 2289882..2290544 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUW39_RS10855 2290568..2291224 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
HUW39_RS10860 2291326..2291556 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUW39_RS10865 2291695..2292069 + 375 WP_000204705.1 CopC domain-containing protein YobA -
HUW39_RS10870 2292073..2292945 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
HUW39_RS10875 2292958..2293299 + 342 WP_000976481.1 YebY family protein -
- 2293327..2293598 - 272 - - Antitoxin
- 2293457..2293560 + 104 - - Toxin
HUW39_RS10880 2293695..2294351 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
HUW39_RS10885 2294352..2294543 - 192 WP_001296140.1 YebW family protein -
HUW39_RS10890 2294648..2294884 - 237 WP_001295499.1 YebV family protein -
HUW39_RS10895 2295002..2296441 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2286017..2309437 23420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T162520 NZ_CP056036:2293457-2293560 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT162520 NZ_CP056036:c2293598-2293327 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References