Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1934186..1934330 Replicon chromosome
Accession NZ_CP055509
Organism Klebsiella pneumoniae strain RHBSTW-00472

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1934222..1934324 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1934186..1934330 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV207_RS09475 1929316..1931376 + 2061 WP_004151449.1 oligopeptidase B -
HV207_RS09480 1931380..1932039 - 660 WP_021440386.1 exodeoxyribonuclease X -
HV207_RS09485 1932118..1932348 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV207_RS09490 1932461..1932835 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV207_RS09495 1932839..1933708 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HV207_RS09500 1933725..1934063 + 339 WP_002911404.1 YebY family protein -
- 1934186..1934330 - 145 - - Antitoxin
- 1934222..1934324 + 103 - - Toxin
HV207_RS09505 1934457..1934816 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
HV207_RS09510 1934815..1935294 + 480 WP_064147222.1 lysis protein -
HV207_RS09515 1936083..1936274 + 192 WP_064147221.1 hypothetical protein -
HV207_RS09520 1936225..1937589 + 1365 WP_181247924.1 hypothetical protein -
HV207_RS09525 1937839..1938267 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
HV207_RS09530 1938277..1938558 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162394 NZ_CP055509:1934222-1934324 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT162394 NZ_CP055509:c1934330-1934186 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References