Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1682369..1682908 Replicon chromosome
Accession NZ_CP055302
Organism Mannheimia pernigra strain 16CN0041

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HV561_RS08620 Protein ID WP_176808559.1
Coordinates 1682369..1682638 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HV561_RS08625 Protein ID WP_176808560.1
Coordinates 1682642..1682908 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV561_RS08600 1677607..1678323 - 717 WP_176808556.1 phage minor tail protein L -
HV561_RS08605 1678323..1678651 - 329 Protein_1645 phage tail protein -
HV561_RS08610 1678651..1681953 - 3303 WP_176808557.1 tape measure protein -
HV561_RS08615 1682017..1682292 - 276 WP_176808558.1 hypothetical protein -
HV561_RS08620 1682369..1682638 - 270 WP_176808559.1 type II toxin-antitoxin system YafQ family toxin Toxin
HV561_RS08625 1682642..1682908 - 267 WP_176808560.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HV561_RS08630 1682972..1683202 - 231 WP_176808561.1 DUF4035 domain-containing protein -
HV561_RS08635 1683247..1683648 - 402 WP_176808562.1 hypothetical protein -
HV561_RS08640 1683731..1684372 - 642 WP_176808563.1 hypothetical protein -
HV561_RS08645 1684404..1684799 - 396 WP_176808564.1 phage tail protein -
HV561_RS08650 1684796..1685320 - 525 WP_176808565.1 phage tail protein -
HV561_RS08655 1685327..1685629 - 303 WP_176808566.1 phage tail protein -
HV561_RS08660 1685622..1685945 - 324 WP_176808567.1 DUF2190 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1671947..1741120 69173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-77)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10269.94 Da        Isoelectric Point: 7.3813

>T162318 WP_176808559.1 NZ_CP055302:c1682638-1682369 [Mannheimia pernigra]
MLQISPTNAYKRDFKKIATALVGSSEYVEVMYCLIHQLPLAEKYKDHPLHGEWQGFRDCHIKPDLVLIYAVENNLLRLVR
LGSHSELFG

Download         Length: 270 bp

>T162318 NZ_CP071731:c1582415-1582137 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTAGGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9954.39 Da        Isoelectric Point: 5.7656

>AT162318 WP_176808560.1 NZ_CP055302:c1682908-1682642 [Mannheimia pernigra]
MATINDAFSFRTNTEIKNIAFDVIKNYGMTPSQVFNMFLTEIAKTKTIPLSLNYQPNLETQLAMQEAKSGKNEVYASLND
FHKAMLAE

Download         Length: 267 bp

>AT162318 NZ_CP071731:c1582125-1581820 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTTGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References