Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010727..2010872 Replicon chromosome
Accession NZ_CP055294
Organism Klebsiella pneumoniae strain KP55

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010763..2010865 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010727..2010872 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW33_RS09850 (HUW33_09845) 2005857..2007917 + 2061 WP_004151449.1 oligopeptidase B -
HUW33_RS09855 (HUW33_09850) 2007921..2008580 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUW33_RS09860 (HUW33_09855) 2008659..2008889 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUW33_RS09865 (HUW33_09860) 2009002..2009376 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUW33_RS09870 (HUW33_09865) 2009380..2010249 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HUW33_RS09875 (HUW33_09870) 2010266..2010604 + 339 WP_002911404.1 YebY family protein -
- 2010727..2010872 - 146 - - Antitoxin
- 2010763..2010865 + 103 - - Toxin
HUW33_RS09880 (HUW33_09875) 2011240..2011383 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUW33_RS09885 (HUW33_09880) 2011488..2012456 - 969 WP_004151446.1 VirK/YbjX family protein -
HUW33_RS09890 (HUW33_09885) 2012613..2013266 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HUW33_RS09895 (HUW33_09890) 2013263..2013454 - 192 WP_002911395.1 YebW family protein -
HUW33_RS09900 (HUW33_09895) 2013552..2013791 - 240 WP_002911393.1 YebV family protein -
HUW33_RS09905 (HUW33_09900) 2013907..2015340 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162285 NZ_CP055294:2010763-2010865 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT162285 NZ_CP055294:c2010872-2010727 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References