Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1900552..1900697 Replicon chromosome
Accession NZ_CP055293
Organism Klebsiella pneumoniae strain 200

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1900588..1900690 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1900552..1900697 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWA76_RS09210 1895682..1897742 + 2061 WP_004151449.1 oligopeptidase B -
HWA76_RS09215 1897746..1898405 - 660 WP_002911407.1 exodeoxyribonuclease X -
HWA76_RS09220 1898484..1898714 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HWA76_RS09225 1898827..1899201 + 375 WP_039819395.1 CopC domain-containing protein YobA -
HWA76_RS09230 1899205..1900074 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HWA76_RS09235 1900091..1900429 + 339 WP_002911404.1 YebY family protein -
- 1900552..1900697 - 146 - - Antitoxin
- 1900588..1900690 + 103 - - Toxin
HWA76_RS09240 1901066..1901209 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
HWA76_RS09245 1901314..1902282 - 969 WP_014907334.1 VirK/YbjX family protein -
HWA76_RS09250 1902439..1903092 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
HWA76_RS09255 1903089..1903280 - 192 WP_002911395.1 YebW family protein -
HWA76_RS09260 1903378..1903617 - 240 WP_002911393.1 YebV family protein -
HWA76_RS09265 1903733..1905166 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162266 NZ_CP055293:1900588-1900690 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT162266 NZ_CP055293:c1900697-1900552 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References