Detailed information of TA system TA162214

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 3784805..3785463
• Replicon: chromosome
• Accession: NZ_CP055276
• Organism: Enterobacter mori strain CX01

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: HUI94_RS17935
• Protein ID: WP_155061777.1
• Coordinates: 3784805..3785125 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: HUI94_RS17940
• Protein ID: WP_131024340.1
• Coordinates: 3785146..3785463 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HUI94_RS17900 (HUI94_17875)	3780077..3780616	+	540	WP_010434257.1	3-isopropylmalate dehydratase small subunit	-
HUI94_RS17905 (HUI94_17880)	3780704..3781714	+	1011	WP_100166232.1	TauD/TfdA family dioxygenase	-
HUI94_RS17910 (HUI94_17885)	3781820..3782212	-	393	WP_042713388.1	hypothetical protein	-
HUI94_RS17915 (HUI94_17890)	3782848..3783174	-	327	WP_218400530.1	hypothetical protein	-
HUI94_RS17920 (HUI94_17895)	3783453..3784253	+	801	WP_218400532.1	nucleotidyltransferase domain-containing protein	-
HUI94_RS17925 (HUI94_17900)	3784304..3784506	+	203	Protein_3496	IS3 family transposase	-
HUI94_RS17930 (HUI94_17905)	3784466..3784666	+	201	WP_218402633.1	hypothetical protein	-
HUI94_RS17935 (HUI94_17910)	3784805..3785125	-	321	WP_155061777.1	TA system toxin CbtA family protein	Toxin
HUI94_RS17940 (HUI94_17915)	3785146..3785463	-	318	WP_131024340.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
HUI94_RS17945 (HUI94_17920)	3785482..3785703	-	222	WP_131024341.1	DUF987 domain-containing protein	-
HUI94_RS17950 (HUI94_17925)	3785712..3786188	-	477	WP_218400534.1	RadC family protein	-
HUI94_RS17955 (HUI94_17930)	3786204..3786662	-	459	WP_218400536.1	antirestriction protein	-
HUI94_RS17960 (HUI94_17935)	3786758..3786973	-	216	Protein_3503	DUF905 domain-containing protein	-
HUI94_RS17965 (HUI94_17940)	3787051..3787461	-	411	WP_218400540.1	hypothetical protein	-
HUI94_RS17970 (HUI94_17945)	3787528..3787965	-	438	WP_218400542.1	hypothetical protein	-
HUI94_RS17975 (HUI94_17950)	3788007..3788543	-	537	WP_218400544.1	DUF4339 domain-containing protein	-
HUI94_RS17980 (HUI94_17955)	3788569..3789279	-	711	WP_218400546.1	DeoR family transcriptional regulator	-
HUI94_RS17985 (HUI94_17960)	3789488..3789649	-	162	Protein_3508	DUF945 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3781820..3810480	28660

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-104)

Antitoxin

• Antitoxin CbeA (5-104)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12116.11 Da
• Isoelectric Point: 8.0358

>T162214 WP_155061777.1 NZ_CP055276:c3785125-3784805 [Enterobacter mori]
MKTLPATTLRAAKPCPSPVIVWQMLLSRLLDQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Nucleotide

• Length: 321 bp

>T162214 NZ_CP071690:c2693598-2693495 [Salmonella sp. SAL-020]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11961.42 Da
• Isoelectric Point: 6.6287

>AT162214 WP_131024340.1 NZ_CP055276:c3785463-3785146 [Enterobacter mori]
MSNITWGLQRDTTPRLGARLVQEGNQLHYLADRASITGKFSDTECRKLDETFPHFISQMESMLTTGEMNPRHTHSVTLYH
NGFTCEADTLGSCGYIYITVYPTQR

Nucleotide

• Length: 318 bp

>AT162214 NZ_CP071690:2693493-2693638 [Salmonella sp. SAL-020]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG