162213

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3496035..3496692 Replicon chromosome
Accession NZ_CP055276
Organism Enterobacter mori strain CX01

Toxin (Protein)


Gene name cptA Uniprot ID A0A6S5Y1H5
Locus tag HUI94_RS16580 Protein ID WP_010435320.1
Coordinates 3496282..3496692 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HUI94_RS16575 Protein ID WP_042716098.1
Coordinates 3496035..3496301 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUI94_RS16550 (HUI94_16525) 3491206..3492639 - 1434 WP_100166360.1 6-phospho-beta-glucosidase BglA -
HUI94_RS16555 (HUI94_16530) 3492757..3493488 - 732 WP_042719286.1 MurR/RpiR family transcriptional regulator -
HUI94_RS16560 (HUI94_16535) 3493539..3493850 + 312 WP_100166359.1 N(4)-acetylcytidine aminohydrolase -
HUI94_RS16565 (HUI94_16540) 3494016..3494675 + 660 WP_003863433.1 hemolysin III family protein -
HUI94_RS16570 (HUI94_16545) 3494760..3495740 - 981 WP_100166358.1 tRNA-modifying protein YgfZ -
HUI94_RS16575 (HUI94_16550) 3496035..3496301 + 267 WP_042716098.1 FAD assembly factor SdhE Antitoxin
HUI94_RS16580 (HUI94_16555) 3496282..3496692 + 411 WP_010435320.1 protein YgfX Toxin
HUI94_RS16585 (HUI94_16560) 3496700..3497221 - 522 WP_010435318.1 flavodoxin FldB -
HUI94_RS16590 (HUI94_16565) 3497323..3498219 + 897 WP_218400370.1 site-specific tyrosine recombinase XerD -
HUI94_RS16595 (HUI94_16570) 3498248..3498961 + 714 WP_214598173.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HUI94_RS16600 (HUI94_16575) 3498967..3500700 + 1734 WP_042716101.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16173.06 Da        Isoelectric Point: 11.5020

>T162213 WP_010435320.1 NZ_CP055276:3496282-3496692 [Enterobacter mori]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEIVGTPWMLSVGMMLRLRQPEGGRRQHLWLAADSMDAAEWRDLRRMMLQQPTQD

Download         Length: 411 bp

>T162213 NZ_CP071690:c2444130-2443975 [Salmonella sp. SAL-020]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10528.99 Da        Isoelectric Point: 5.6254

>AT162213 WP_042716098.1 NZ_CP055276:3496035-3496301 [Enterobacter mori]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT162213 NZ_CP071690:2444142-2444200 [Salmonella sp. SAL-020]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6S5Y1H5

Antitoxin

Source ID Structure

References