Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3410043..3410824 Replicon chromosome
Accession NZ_CP055276
Organism Enterobacter mori strain CX01

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag HUI94_RS16125 Protein ID WP_100166398.1
Coordinates 3410333..3410824 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag HUI94_RS16120 Protein ID WP_042713858.1
Coordinates 3410043..3410336 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUI94_RS16105 (HUI94_16080) 3407029..3407343 - 315 WP_010435531.1 lipoprotein -
HUI94_RS16110 (HUI94_16085) 3407519..3408151 + 633 WP_218400321.1 response regulator transcription factor -
HUI94_RS16115 (HUI94_16090) 3408148..3409941 + 1794 WP_218400323.1 hybrid sensor histidine kinase/response regulator -
HUI94_RS16120 (HUI94_16095) 3410043..3410336 + 294 WP_042713858.1 DUF1778 domain-containing protein Antitoxin
HUI94_RS16125 (HUI94_16100) 3410333..3410824 + 492 WP_100166398.1 GNAT family N-acetyltransferase Toxin
HUI94_RS16130 (HUI94_16105) 3410973..3411410 - 438 WP_245004285.1 DUF523 domain-containing protein -
HUI94_RS16135 (HUI94_16110) 3411686..3412108 + 423 WP_245004286.1 DUF3450 domain-containing protein -
HUI94_RS16145 (HUI94_16120) 3412420..3413133 - 714 WP_100166396.1 DUF554 domain-containing protein -
HUI94_RS16150 (HUI94_16125) 3413315..3415450 + 2136 WP_218400325.1 ornithine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(87-144)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 17482.27 Da        Isoelectric Point: 7.2653

>T162212 WP_100166398.1 NZ_CP055276:3410333-3410824 [Enterobacter mori]
MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQASGASRTFVCCGGDSNVLAYYSLASSAVTTNTAPGRFRRNMPDP
IPVVVLGRLAVDQSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMILMVTLGDLV
ASI

Download         Length: 492 bp

>T162212 NZ_CP071690:c989046-988519 [Salmonella sp. SAL-020]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTACTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10941.57 Da        Isoelectric Point: 9.9156

>AT162212 WP_042713858.1 NZ_CP055276:3410043-3410336 [Enterobacter mori]
MPAANTMAVKRETLNLRIRPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLARLDQAPAPN
AALRKTMQTPAPWEREK

Download         Length: 294 bp

>AT162212 NZ_CP071690:c989333-989043 [Salmonella sp. SAL-020]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTGCGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References