Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2260519..2261052 Replicon chromosome
Accession NZ_CP055265
Organism Agrobacterium vitis strain CG412

Toxin (Protein)


Gene name yoeB Uniprot ID A0A368NHT3
Locus tag AVCG412_RS10770 Protein ID WP_060719920.1
Coordinates 2260786..2261052 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A368NJR8
Locus tag AVCG412_RS10765 Protein ID WP_060719919.1
Coordinates 2260519..2260782 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVCG412_RS10745 (AVCG412_10715) 2255960..2257066 + 1107 WP_156545099.1 branched-chain amino acid ABC transporter substrate-binding protein -
AVCG412_RS10750 (AVCG412_10720) 2257222..2258091 + 870 WP_060719916.1 aldose 1-epimerase family protein -
AVCG412_RS10755 (AVCG412_10725) 2258088..2258750 + 663 WP_060719917.1 chloramphenicol phosphotransferase -
AVCG412_RS10760 (AVCG412_10730) 2258770..2260464 + 1695 WP_060719918.1 adenine deaminase -
AVCG412_RS10765 (AVCG412_10735) 2260519..2260782 + 264 WP_060719919.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AVCG412_RS10770 (AVCG412_10740) 2260786..2261052 + 267 WP_060719920.1 Txe/YoeB family addiction module toxin Toxin
AVCG412_RS10775 (AVCG412_10745) 2261375..2263042 - 1668 WP_060719960.1 alpha glucosidase -
AVCG412_RS10780 (AVCG412_10750) 2263318..2264385 + 1068 WP_060719921.1 glycosyltransferase family 1 protein -
AVCG412_RS10785 (AVCG412_10755) 2264387..2265811 - 1425 WP_015916784.1 ribosome biogenesis GTPase Der -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10331.74 Da        Isoelectric Point: 8.4926

>T162204 WP_060719920.1 NZ_CP055265:2260786-2261052 [Agrobacterium vitis]
MLVAFTDEGWEDYCFWQETDPKTAQRINALLKDTKRHPFSGIGKPEPLKGQFKGFWSRRISQEHRLVYAVKGQDGDQVLI
VAQCRYHY

Download         Length: 267 bp

>T162204 NZ_CP071686:4490228-4490539 [Salmonella sp. SAL-007]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACACTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATGATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9582.93 Da        Isoelectric Point: 5.1358

>AT162204 WP_060719919.1 NZ_CP055265:2260519-2260782 [Agrobacterium vitis]
MDTVFFSKARAELAGLLDKVNEDASAVEIVRRDKPSAVLMSKEEYESMVETLHLLSSPANASRLLKAKQAIEAGRFAPRH
LPDLDDA

Download         Length: 264 bp

>AT162204 NZ_CP071686:4490536-4490982 [Salmonella sp. SAL-007]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A368NHT3

Antitoxin

Source ID Structure
AlphaFold DB A0A368NJR8

References