Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 7900312..7901842 Replicon chromosome
Accession NZ_CP055233
Organism Bradyrhizobium diazoefficiens strain 113-2

Toxin (Protein)


Gene name rlegT Uniprot ID A0A562QN92
Locus tag HUW42_RS36930 Protein ID WP_018647871.1
Coordinates 7900922..7901842 (+) Length 307 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A810CIT3
Locus tag HUW42_RS36925 Protein ID WP_026312796.1
Coordinates 7900312..7900932 (+) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW42_RS36910 7896677..7896904 + 228 WP_131234255.1 hypothetical protein -
HUW42_RS36915 7896867..7899377 + 2511 WP_011084731.1 AAA family ATPase -
HUW42_RS36920 7899352..7900098 + 747 WP_018647872.1 DCL family protein -
HUW42_RS36925 7900312..7900932 + 621 WP_026312796.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
HUW42_RS36930 7900922..7901842 + 921 WP_018647871.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
HUW42_RS36935 7901920..7903224 + 1305 WP_011084727.1 SIR2 family protein -
HUW42_RS36940 7903232..7905340 + 2109 WP_011084726.1 DUF87 domain-containing protein -
HUW42_RS36945 7905349..7905867 + 519 Protein_7343 exonuclease subunit SbcD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-264)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-56)


Sequences

Toxin        


Download         Length: 307 a.a.        Molecular weight: 34027.14 Da        Isoelectric Point: 5.2727

>T162057 WP_018647871.1 NZ_CP055233:7900922-7901842 [Bradyrhizobium diazoefficiens]
MAREPRNIGASVRARLLDRARAERSDFQILLTRYALERLLYRLSASPHRDRFILKGAMLFVTWIADPFRPTRDLDLLGHG
DRDTEAIAETFRAICAQPVVDDGVTFDVAALMATPIREELEYGGVRVRTTATIAGARIPIQVDIGFGDAITPAAVEIDYP
TLLDAPTPHLRAYPVETVVAEKFAALVTLGVANSRLKDFYDLWVISRTFELRRAALAEAIQRTFERRGTVLPSVVPVGLT
DEFAETWAAQWRAFLERDRMAAAPDAFAVTVADLRLFLMPLVVGLKEERIWPPSGPWSPGAAIDEA

Download         Length: 921 bp

>T162057 NZ_CP071521:183650-183757 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 23385.28 Da        Isoelectric Point: 10.0691

>AT162057 WP_026312796.1 NZ_CP055233:7900312-7900932 [Bradyrhizobium diazoefficiens]
MPSTSAQRLRALDLLKTRGMLRLKDFIAEGIGPETLARLVREEAVVRPARGLYQLPDAHLEAAHTLAEAAVLVPKGVVCL
TSALQYHELTLQMPSAVWMAIDRSAWRPKIDYPPIRFVRFTGSALTEGIERHRIENVDVPITDPARTIVDCFRYRTKIGL
DVAMEGLREGLRRRRCKPDQLWHYARKARVWSVMRPYVEAMVSDGA

Download         Length: 621 bp

>AT162057 NZ_CP071521:c183601-183535 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A562QN92

Antitoxin

Source ID Structure
AlphaFold DB A0A810CIT3

References