Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 725385..726051 | Replicon | chromosome |
Accession | NZ_CP055227 | ||
Organism | Erwinia amylovora strain Ea1189 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A830ZTB8 |
Locus tag | GTU81_RS03325 | Protein ID | WP_004161808.1 |
Coordinates | 725632..726051 (+) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | D4HWC2 |
Locus tag | GTU81_RS03320 | Protein ID | WP_004155593.1 |
Coordinates | 725385..725651 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GTU81_RS03300 | 721895..722587 | + | 693 | WP_004155586.1 | SDR family oxidoreductase | - |
GTU81_RS03305 | 722692..723300 | - | 609 | WP_004155587.1 | HD domain-containing protein | - |
GTU81_RS03310 | 723513..724172 | + | 660 | WP_004155588.1 | hemolysin III family protein | - |
GTU81_RS03315 | 724173..725159 | - | 987 | WP_004155590.1 | tRNA-modifying protein YgfZ | - |
GTU81_RS03320 | 725385..725651 | + | 267 | WP_004155593.1 | FAD assembly factor SdhE | Antitoxin |
GTU81_RS03325 | 725632..726051 | + | 420 | WP_004161808.1 | hypothetical protein | Toxin |
GTU81_RS03330 | 726169..726687 | - | 519 | WP_004155596.1 | flavodoxin FldB | - |
GTU81_RS03335 | 726917..727870 | - | 954 | WP_004155597.1 | DMT family transporter | - |
GTU81_RS03340 | 728380..730059 | - | 1680 | WP_004155599.1 | type III effector | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 16366.46 Da Isoelectric Point: 11.9444
>T162045 WP_004161808.1 NZ_CP055227:725632-726051 [Erwinia amylovora]
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
Download Length: 420 bp
>T162045 NZ_CP071503:1072720-1073214 [Shewanella sp. FJAT-51800]
ATGAATACCGTGCTGCTCGACAAAGATAAACACGATAGAAACCGATTCAATTGTGGTATCGACGCGCTGAATAACTACTT
CAAAGTGATGGCCAGCCAGCAAGCCAAAAAAGACAATACCCGAACTTTTGTGTTGGAAGATGACACCGATAACTCGGCCG
TGATTGGCTTTTATACGCTAACCATGACCCCGATCGACCTGAACGCCTTACCGATCAAACTGCAGAAAAAACACCCGTCA
TCTATGTCCGGCGGACTCATCGCCCGCTTAGCCGTAGATAATCGTTACCAAGGCCGAGGATTCGGCGAATGGTTACTGAT
CGACGCCCTGCGTAAATTACTTGCCGCCAGCGACACCGTCGCCTTTCCCATCGTAATCGTAGATGCCAAAGACGGCGCCG
CGCACTTTTGCGAAAAATATGGCTTCACCGCATTTCAAGACACTGAAAACAAACTCTTCATCACCATCGCAGACATCCGC
GCCAGCTTGAGTTAA
ATGAATACCGTGCTGCTCGACAAAGATAAACACGATAGAAACCGATTCAATTGTGGTATCGACGCGCTGAATAACTACTT
CAAAGTGATGGCCAGCCAGCAAGCCAAAAAAGACAATACCCGAACTTTTGTGTTGGAAGATGACACCGATAACTCGGCCG
TGATTGGCTTTTATACGCTAACCATGACCCCGATCGACCTGAACGCCTTACCGATCAAACTGCAGAAAAAACACCCGTCA
TCTATGTCCGGCGGACTCATCGCCCGCTTAGCCGTAGATAATCGTTACCAAGGCCGAGGATTCGGCGAATGGTTACTGAT
CGACGCCCTGCGTAAATTACTTGCCGCCAGCGACACCGTCGCCTTTCCCATCGTAATCGTAGATGCCAAAGACGGCGCCG
CGCACTTTTGCGAAAAATATGGCTTCACCGCATTTCAAGACACTGAAAACAAACTCTTCATCACCATCGCAGACATCCGC
GCCAGCTTGAGTTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10498.07 Da Isoelectric Point: 6.4605
>AT162045 WP_004155593.1 NZ_CP055227:725385-725651 [Erwinia amylovora]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
Download Length: 267 bp
>AT162045 NZ_CP071503:1072448-1072723 [Shewanella sp. FJAT-51800]
ATGGCCTCAACATTGCCGCGTATTACCGCCAGAGTAGACCTTGATACCCAAGATTTACTGACCAAAGCCGCTGCTATTGC
CGGTATGTCTAGCATTAACTCTTTTGTGCTAAACGCCGCCATTGAAAAAGCTAAGCAGGTGATTGAGCGTGAAGAAACTC
TCAAACTCAGCCGAATTGACGCTATGGCACTGATGGATGCACTCGACCAACCCGCCAAGGCCAATACCAAACTGCAAGCC
GCCGCCAAGCGCTACGATGGTAAAAGCCAGCAATGA
ATGGCCTCAACATTGCCGCGTATTACCGCCAGAGTAGACCTTGATACCCAAGATTTACTGACCAAAGCCGCTGCTATTGC
CGGTATGTCTAGCATTAACTCTTTTGTGCTAAACGCCGCCATTGAAAAAGCTAAGCAGGTGATTGAGCGTGAAGAAACTC
TCAAACTCAGCCGAATTGACGCTATGGCACTGATGGATGCACTCGACCAACCCGCCAAGGCCAATACCAAACTGCAAGCC
GCCGCCAAGCGCTACGATGGTAAAAGCCAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A830ZTB8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A831A3F0 |