Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4815982..4816535 Replicon chromosome
Accession NZ_CP055224
Organism Pectobacterium atrosepticum strain Green1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HLB43_RS21380 Protein ID WP_215216066.1
Coordinates 4815982..4816296 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HLB43_RS21385 Protein ID WP_215216067.1
Coordinates 4816299..4816535 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HLB43_RS21370 (HLB43_21360) 4812902..4813648 + 747 WP_215216064.1 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ -
HLB43_RS21375 (HLB43_21365) 4813790..4815685 + 1896 WP_215216065.1 5'-nucleotidase C-terminal domain-containing protein -
HLB43_RS22295 4815812..4815961 + 150 Protein_4206 transposase -
HLB43_RS21380 (HLB43_21370) 4815982..4816296 - 315 WP_215216066.1 CcdB family protein Toxin
HLB43_RS21385 (HLB43_21375) 4816299..4816535 - 237 WP_215216067.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
HLB43_RS21390 (HLB43_21380) 4816820..4818163 - 1344 WP_215216068.1 NADP-specific glutamate dehydrogenase -
HLB43_RS21395 (HLB43_21385) 4818456..4818893 - 438 WP_011091695.1 universal stress protein UspA -
HLB43_RS21400 (HLB43_21390) 4819558..4819893 + 336 WP_011091694.1 universal stress protein UspB -
HLB43_RS21405 (HLB43_21395) 4820020..4821525 - 1506 WP_215216069.1 inorganic phosphate transporter PitA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11653.67 Da        Isoelectric Point: 7.9859

>T162026 WP_215216066.1 NZ_CP055224:c4816296-4815982 [Pectobacterium atrosepticum]
MRFTVYSNTGKSAVYPLLLDVTSDIIGQLNRRIVIPLLPVEKYPGSTRPERLVPLVRLTDDKEYAVMTHEMASIPVRSLG
VVFCDASLYRTQIKAAIDFLLDGI

Download         Length: 315 bp

>T162026 NZ_CP071489:c1860049-1859714 [Glaesserella parasuis]
ATGTCAGGAATTATCAACCAAATCATCATTACAGATAATTTTTCAAAGTGGCTAGATGGTTTAAAAAATCCTATTGCTAA
AGCAACAGTGGCAAGAAGAATTAAGAATACAGTAAAAGGTAATTTTGATGATCATAAAGCGCTTGCAGGTACTGGTGGAC
TTTATGAAATGCGAATAGCGACAGGCGCTGGTTATCGAATTTACTATGCACAGCAGGGCGATGTTATTTATATTCTGTTA
CAAGGTGGTGATAAATCAACACAGCAAGTCGATATTGAGAAAGCGAAAGCATTGTGGGCAGAATTAAAACAGACAGGAGG
AAGTAATGAATATTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8865.80 Da        Isoelectric Point: 4.8040

>AT162026 WP_215216067.1 NZ_CP055224:c4816535-4816299 [Pectobacterium atrosepticum]
MATTPRATQSVTMTVERSLLSRAREAGINLSATLTAALDAELRQYEAKKWQEENSEALEALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT162026 NZ_CP071489:c1859706-1859410 [Glaesserella parasuis]
ATGGCAGAAAAACACGGTTTACGTCCTTTTGATGTCGCTGAATTTTTGGATAACGAAGAAACAATACAAGCCTATTTAGC
AGAAGTATTAAAAGAGGGCGATCAAGATGAGTTTTTGGAAGCCCTTAATGATGTAGCAAGAGCAAGGGGGATCGCAGAAC
TTGCGAAGCAAACGGGGTTAGGTAGAGAAAGTTTATATAAAACCCTATCTAAAGGAAGTAAACCTCGTTTTGAAACTATT
CAAAAAATTTTAGGAGCATTTAATCTTGTGCTTATCCCACAAATAAAAAATAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References