Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 3583400..3584025 | Replicon | chromosome |
Accession | NZ_CP055224 | ||
Organism | Pectobacterium atrosepticum strain Green1 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | Q6D810 |
Locus tag | HLB43_RS15895 | Protein ID | WP_011092758.1 |
Coordinates | 3583822..3584025 (+) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | Q6D809 |
Locus tag | HLB43_RS15890 | Protein ID | WP_010282247.1 |
Coordinates | 3583400..3583768 (+) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HLB43_RS15875 (HLB43_15870) | 3579058..3582186 | + | 3129 | WP_011092760.1 | efflux RND transporter permease subunit | - |
HLB43_RS15880 (HLB43_15875) | 3582392..3582640 | + | 249 | WP_011092759.1 | type B 50S ribosomal protein L31 | - |
HLB43_RS15885 (HLB43_15880) | 3582658..3582801 | + | 144 | WP_005976091.1 | type B 50S ribosomal protein L36 | - |
HLB43_RS15890 (HLB43_15885) | 3583400..3583768 | + | 369 | WP_010282247.1 | Hha toxicity modulator TomB | Antitoxin |
HLB43_RS15895 (HLB43_15890) | 3583822..3584025 | + | 204 | WP_011092758.1 | HHA domain-containing protein | Toxin |
HLB43_RS15905 (HLB43_15900) | 3584769..3585089 | + | 321 | WP_011092757.1 | MGMT family protein | - |
HLB43_RS15910 (HLB43_15905) | 3585109..3585690 | - | 582 | WP_011092756.1 | YbaY family lipoprotein | - |
HLB43_RS15915 (HLB43_15910) | 3585903..3586766 | + | 864 | WP_011092755.1 | acyl-CoA thioesterase II | - |
HLB43_RS15920 (HLB43_15915) | 3586884..3588170 | - | 1287 | WP_039290645.1 | ammonium transporter AmtB | - |
HLB43_RS15925 (HLB43_15920) | 3588210..3588548 | - | 339 | WP_002208627.1 | P-II family nitrogen regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8159.55 Da Isoelectric Point: 8.9008
>T162019 WP_011092758.1 NZ_CP055224:3583822-3584025 [Pectobacterium atrosepticum]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKIPTAVWRYVR
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKIPTAVWRYVR
Download Length: 204 bp
>T162019 NZ_CP071489:468708-468875 [Glaesserella parasuis]
ATGATAAAACTTCTCAAAAAGAACGGTTGGGAGCTAGATAGCATAGTCGGTAGCCACCACCACTTTGAGAAGAAAAATCA
AAAGGGAGCAGGCAAAGTGACTGTTCCCCACCCGAGAAAAGACTTAGGCTTTCTCGAAAAGAAAATCAGAAAACAAGCGG
GGCTGTAA
ATGATAAAACTTCTCAAAAAGAACGGTTGGGAGCTAGATAGCATAGTCGGTAGCCACCACCACTTTGAGAAGAAAAATCA
AAAGGGAGCAGGCAAAGTGACTGTTCCCCACCCGAGAAAAGACTTAGGCTTTCTCGAAAAGAAAATCAGAAAACAAGCGG
GGCTGTAA
Antitoxin
Download Length: 123 a.a. Molecular weight: 14046.80 Da Isoelectric Point: 4.4787
>AT162019 WP_010282247.1 NZ_CP055224:3583400-3583768 [Pectobacterium atrosepticum]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENICTPAKT
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENICTPAKT
Download Length: 369 bp
>AT162019 NZ_CP071489:468914-469321 [Glaesserella parasuis]
ATGTTATACCCACTCATTTTTGAACAAGTTTCCGACGGCTATGTCGTTGCTATCCCAGATATTGACGGCTGTTATTCTGC
TGGAGATACCCTAGAAGAAACTTATAGCAACGTAAAACAAGCTATAGCACTTCATCTCGAATCTGTCGTCAAAGATGGGG
GAGAAATTCCAACGCCTACCGCTATCGAAAACCACAAAAACGACCCTGATTTAGACGGTCATAACGTATTTTTCGGTGTG
GTTGATGTCGATTTATCCCACCTAATGGGCAAAGCAGAGAAAATCAACATCACCCTCCCTAGCTATCTCATCAAACGCAT
TGATGATTTTGTTGCGGTTCACAAAGAGTATAAAAACCGTAGCAACTTCTTAGCTAAAATCGCAGCGGATAAAATCTTAA
CCGCTTAA
ATGTTATACCCACTCATTTTTGAACAAGTTTCCGACGGCTATGTCGTTGCTATCCCAGATATTGACGGCTGTTATTCTGC
TGGAGATACCCTAGAAGAAACTTATAGCAACGTAAAACAAGCTATAGCACTTCATCTCGAATCTGTCGTCAAAGATGGGG
GAGAAATTCCAACGCCTACCGCTATCGAAAACCACAAAAACGACCCTGATTTAGACGGTCATAACGTATTTTTCGGTGTG
GTTGATGTCGATTTATCCCACCTAATGGGCAAAGCAGAGAAAATCAACATCACCCTCCCTAGCTATCTCATCAAACGCAT
TGATGATTTTGTTGCGGTTCACAAAGAGTATAAAAACCGTAGCAACTTCTTAGCTAAAATCGCAGCGGATAAAATCTTAA
CCGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J5XPH8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A086EI31 |