Detailed information of TA system TA162017

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2888160..2889070
• Replicon: chromosome
• Accession: NZ_CP055224
• Organism: Pectobacterium atrosepticum strain Green1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HLB43_RS12925
• Protein ID: WP_039291191.1
• Coordinates: 2888160..2888630 (-)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HLB43_RS12930
• Protein ID: WP_039291190.1
• Coordinates: 2888627..2889070 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HLB43_RS12905 (HLB43_12900)	2883244..2884176	-	933	WP_039291199.1	tRNA dihydrouridine(16) synthase DusC	-
HLB43_RS12910 (HLB43_12905)	2884420..2885091	+	672	WP_039291197.1	epoxyqueuosine reductase QueH	-
HLB43_RS12915 (HLB43_12910)	2885138..2886733	-	1596	WP_039291195.1	ABC transporter substrate-binding protein	-
HLB43_RS12920 (HLB43_12915)	2886874..2888103	+	1230	WP_039291193.1	peptidase T	-
HLB43_RS12925 (HLB43_12920)	2888160..2888630	-	471	WP_039291191.1	RES family NAD+ phosphorylase	Toxin
HLB43_RS12930 (HLB43_12925)	2888627..2889070	-	444	WP_039291190.1	DUF2384 domain-containing protein	Antitoxin
HLB43_RS12935 (HLB43_12930)	2889106..2889243	+	138	WP_226302305.1	hypothetical protein	-
HLB43_RS12940 (HLB43_12935)	2889284..2890735	-	1452	WP_039291188.1	ATP-dependent RNA helicase RhlE	-
HLB43_RS12945 (HLB43_12940)	2891013..2891867	-	855	WP_048018368.1	ABC transporter ATP-binding protein	-
HLB43_RS12950 (HLB43_12945)	2891880..2892911	-	1032	WP_039291186.1	iron ABC transporter permease	-
HLB43_RS12955 (HLB43_12950)	2892904..2893893	-	990	WP_039291185.1	iron ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-145)

Antitoxin

• Antitoxin Xre (16-147)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17637.08 Da
• Isoelectric Point: 4.4093

>T162017 WP_039291191.1 NZ_CP055224:c2888630-2888160 [Pectobacterium atrosepticum]
MILYRLTKTKYLSTAWTGYGAKEAGGRWNSIGTSMVYVSETASLAMLETLVHLHAAQILDYYTLMRIDVPEDQIQSADMD
ELPDNWAAEEAPPDLAVYGDAWIFTKGSIALRVPSALSPVEYNYLLNPEHPDFYGIIQMAEIIPFQFDSRLKPDRK

Nucleotide

• Length: 471 bp

>T162017 NZ_CP071487:c1644845-1644345 [Glaesserella parasuis]
ATGAAGAGTAAGTTTATTGAAGAGCCTTTAACGAAGCATCATCAACGTGAAGCCTTTGATTGCGGAAATCTAGAGATGAA
CCGATTTTTTAAACAATACGCTCGGCAATCTCACGAAAAAGGGACATCAAAAACTTACATTAGCCGACACTTAGACAGTC
AACAGATTATCGGATTTTATACAATCACCTTAAGTGCATTAGACCAGCAACACTTACCCGAACTATGCAAAAAACGTTTT
GGCTACCACCCTATTCCGCTCTTTACATTAGCAAGACTTGCAGTGGATATTCGCTATCAAAAACAAGGCATTGGCGGAAT
GCTGTTGGTTAAAGCTCTCAAACGCTGTGCCATCGTTGCCGAACAAGTCTGGGGAATTGGGCTTCTCATTGAAGCAAAAG
ATGAAGACATTTCTCGTTGGTATCAATCTTATGGTGCTATTCCATTGGAAAATATGCCATTAACCTTAATTCTACTCTTT
GATACAATCAAAGGACTTTAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16345.69 Da
• Isoelectric Point: 9.5903

>AT162017 WP_039291190.1 NZ_CP055224:c2889070-2888627 [Pectobacterium atrosepticum]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLEGKVANLIADWAKITQNDLRKMSGIPSTTFSRSVKARFSADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALGGKVPAELMVSETGAYEVMKLLTRLEHGVYS

Nucleotide

• Length: 444 bp

>AT162017 NZ_CP071487:c1645122-1644835 [Glaesserella parasuis]
ATGCCACAAATTGCAAATGCCCTTAACGATAGAATGTCTATTCGCATTAGTACGGAAGACAAGCAGACTTTAATTAGAGC
CGTTGCACTTACCCATACGAATATTACAGAATTTGTATTACAACGCATTTTGCCTAGTGCCAGAGAAATTATTCAGCAGT
ATGATAATCGGCAATTTTCACCGCAAGATCTCTCGTTGATTATGGAATTGCTTGATAATCCGCCGAAAGCTAATACAAAA
CTACAACAAGCGGCGAAATTAGCAAAGGAAAGCTATCATGAAGAGTAA