Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1107303..1107448 Replicon chromosome
Accession NZ_CP055210
Organism Klebsiella pneumoniae strain STEFF_2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1107310..1107412 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1107303..1107448 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ38_RS05460 1102834..1104267 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HUZ38_RS05465 1104383..1104622 + 240 WP_002911393.1 YebV family protein -
HUZ38_RS05470 1104720..1104911 + 192 WP_002911395.1 YebW family protein -
HUZ38_RS05475 1104908..1105561 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
HUZ38_RS05480 1105718..1106686 + 969 WP_004151446.1 VirK/YbjX family protein -
HUZ38_RS05485 1106791..1106934 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1107303..1107448 + 146 - - Antitoxin
- 1107310..1107412 - 103 - - Toxin
HUZ38_RS05490 1107571..1107909 - 339 WP_002911404.1 YebY family protein -
HUZ38_RS05495 1107926..1108795 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HUZ38_RS05500 1108799..1109173 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ38_RS05505 1109286..1109516 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ38_RS05510 1109595..1110254 + 660 WP_020324964.1 exodeoxyribonuclease X -
HUZ38_RS05515 1110258..1112318 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161931 NZ_CP055210:c1107412-1107310 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161931 NZ_CP055210:1107303-1107448 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References