Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1876812..1876957 Replicon chromosome
Accession NZ_CP055186
Organism Klebsiella pneumoniae strain STEFF_14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1876848..1876950 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1876812..1876957 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ42_RS09105 1871942..1874002 + 2061 WP_004151449.1 oligopeptidase B -
HUZ42_RS09110 1874006..1874665 - 660 WP_239592457.1 exodeoxyribonuclease X -
HUZ42_RS09115 1874744..1874974 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ42_RS09120 1875087..1875461 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ42_RS09125 1875465..1876334 + 870 WP_239592458.1 copper homeostasis membrane protein CopD -
HUZ42_RS09130 1876351..1876689 + 339 WP_002911404.1 YebY family protein -
- 1876812..1876957 - 146 - - Antitoxin
- 1876848..1876950 + 103 - - Toxin
HUZ42_RS09135 1877325..1877468 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ42_RS09140 1877573..1878541 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ42_RS09145 1878698..1879351 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
HUZ42_RS09150 1879348..1879539 - 192 WP_002911395.1 YebW family protein -
HUZ42_RS09155 1879637..1879876 - 240 WP_002911393.1 YebV family protein -
HUZ42_RS09160 1879992..1881425 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161838 NZ_CP055186:1876848-1876950 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161838 NZ_CP055186:c1876957-1876812 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References