Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2005963..2006234 Replicon chromosome
Accession NZ_CP055184
Organism Shigella flexneri strain STEFF_16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2006093..2006196 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2005963..2006234 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ44_RS09620 2002518..2003180 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ44_RS09625 2003204..2003860 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HUZ44_RS09630 2003962..2004192 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ44_RS09635 2004331..2004705 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HUZ44_RS09640 2004709..2005581 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
HUZ44_RS09645 2005594..2005935 + 342 WP_000976472.1 YebY family protein -
- 2005963..2006234 - 272 - - Antitoxin
- 2006093..2006196 + 104 - - Toxin
HUZ44_RS09650 2006331..2006987 + 657 Protein_1886 protein-serine/threonine phosphatase -
HUZ44_RS09655 2006988..2007179 - 192 WP_001296140.1 YebW family protein -
HUZ44_RS09660 2007284..2007520 - 237 WP_001295499.1 YebV family protein -
HUZ44_RS09665 2007638..2009077 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1985883..2022072 36189


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161819 NZ_CP055184:2006093-2006196 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161819 NZ_CP055184:c2006234-2005963 [Shigella flexneri]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References