Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1964555..1964826 Replicon chromosome
Accession NZ_CP055181
Organism Shigella flexneri strain STEFF_17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1964685..1964788 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1964555..1964826 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ45_RS09505 1961111..1961773 - 663 WP_000944249.1 exodeoxyribonuclease X -
HUZ45_RS09510 1961796..1962452 - 657 WP_021577595.1 carbon-nitrogen hydrolase family protein YobB -
HUZ45_RS09515 1962554..1962784 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ45_RS09520 1962923..1963297 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ45_RS09525 1963301..1964173 + 873 WP_000879287.1 copper homeostasis membrane protein CopD -
HUZ45_RS09530 1964186..1964527 + 342 WP_000976472.1 YebY family protein -
- 1964555..1964826 - 272 - - Antitoxin
- 1964685..1964788 + 104 - - Toxin
HUZ45_RS09535 1964923..1965579 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
HUZ45_RS09540 1965580..1965771 - 192 WP_001313035.1 YebW family protein -
HUZ45_RS09545 1965876..1966112 - 237 WP_001295499.1 YebV family protein -
HUZ45_RS09550 1966230..1967669 - 1440 WP_096320361.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161800 NZ_CP055181:1964685-1964788 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161800 NZ_CP055181:c1964826-1964555 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References