Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2045586..2045857 Replicon chromosome
Accession NZ_CP055179
Organism Shigella flexneri strain STEFF_18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2045716..2045819 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2045586..2045857 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ46_RS09860 2042141..2042803 - 663 WP_000944256.1 exodeoxyribonuclease X -
HUZ46_RS09865 2042827..2043483 - 657 WP_000011659.1 carbon-nitrogen hydrolase family protein YobB -
HUZ46_RS09870 2043585..2043815 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HUZ46_RS09875 2043954..2044328 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HUZ46_RS09880 2044332..2045204 + 873 WP_106664700.1 copper homeostasis membrane protein CopD -
HUZ46_RS09885 2045217..2045558 + 342 WP_000976472.1 YebY family protein -
- 2045586..2045857 - 272 - - Antitoxin
- 2045716..2045819 + 104 - - Toxin
HUZ46_RS09890 2045954..2046610 + 657 WP_063625304.1 protein-serine/threonine phosphatase -
HUZ46_RS09895 2046611..2046802 - 192 WP_001296140.1 YebW family protein -
HUZ46_RS09900 2046907..2047143 - 237 WP_001295499.1 YebV family protein -
HUZ46_RS09905 2047261..2048700 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T161768 NZ_CP055179:2045716-2045819 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT161768 NZ_CP055179:c2045857-2045586 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAAATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References