Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2465622..2465893 | Replicon | chromosome |
| Accession | NZ_CP055170 | ||
| Organism | Shigella flexneri strain STEFF_22 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2465660..2465763 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2465622..2465893 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUZ49_RS11850 | 2462779..2464218 | + | 1440 | WP_001307251.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| HUZ49_RS11855 | 2464336..2464572 | + | 237 | WP_001295499.1 | YebV family protein | - |
| HUZ49_RS11860 | 2464677..2464868 | + | 192 | WP_001296140.1 | YebW family protein | - |
| HUZ49_RS11865 | 2464869..2465525 | - | 657 | WP_000812724.1 | protein-serine/threonine phosphatase | - |
| - | 2465622..2465893 | + | 272 | - | - | Antitoxin |
| - | 2465660..2465763 | - | 104 | - | - | Toxin |
| HUZ49_RS11870 | 2465921..2466262 | - | 342 | WP_000976492.1 | YebY family protein | - |
| HUZ49_RS11875 | 2466275..2467147 | - | 873 | WP_063108303.1 | copper homeostasis membrane protein CopD | - |
| HUZ49_RS11880 | 2467151..2467525 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| HUZ49_RS11885 | 2467664..2467894 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HUZ49_RS11890 | 2467996..2468652 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HUZ49_RS11895 | 2468676..2469338 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T161712 NZ_CP055170:c2465763-2465660 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT161712 NZ_CP055170:2465622-2465893 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
