Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1963247..1963392 Replicon chromosome
Accession NZ_CP055162
Organism Klebsiella pneumoniae strain STEFF_9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1963283..1963385 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1963247..1963392 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ51_RS09600 1958377..1960437 + 2061 WP_004151449.1 oligopeptidase B -
HUZ51_RS09605 1960441..1961100 - 660 WP_002911407.1 exodeoxyribonuclease X -
HUZ51_RS09610 1961179..1961409 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ51_RS09615 1961522..1961896 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ51_RS09620 1961900..1962769 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
HUZ51_RS09625 1962786..1963124 + 339 WP_016529031.1 YebY family protein -
- 1963247..1963392 - 146 - - Antitoxin
- 1963283..1963385 + 103 - - Toxin
HUZ51_RS09630 1963760..1963903 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ51_RS09635 1964008..1964976 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ51_RS09640 1965133..1965786 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
HUZ51_RS09645 1965783..1965974 - 192 WP_002911395.1 YebW family protein -
HUZ51_RS09650 1966072..1966311 - 240 WP_002911393.1 YebV family protein -
HUZ51_RS09655 1966427..1967860 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161653 NZ_CP055162:1963283-1963385 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161653 NZ_CP055162:c1963392-1963247 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References