Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1035426..1036095 Replicon chromosome
Accession NZ_CP055161
Organism Serratia marcescens strain JW-CZ2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HUW55_RS04820 Protein ID WP_016929976.1
Coordinates 1035673..1036095 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag HUW55_RS04815 Protein ID WP_004931679.1
Coordinates 1035426..1035692 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW55_RS04795 1031960..1032568 - 609 WP_028127691.1 HD domain-containing protein -
HUW55_RS04800 1032752..1033426 + 675 WP_028127690.1 hemolysin III family protein -
HUW55_RS04805 1033577..1034074 + 498 WP_176062698.1 DUF2165 domain-containing protein -
HUW55_RS04810 1034113..1035105 - 993 WP_049300372.1 tRNA-modifying protein YgfZ -
HUW55_RS04815 1035426..1035692 + 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
HUW55_RS04820 1035673..1036095 + 423 WP_016929976.1 protein YgfX Toxin
HUW55_RS04825 1036095..1036793 + 699 WP_016929975.1 two-component system response regulator CreB -
HUW55_RS04830 1036790..1038208 + 1419 WP_016929974.1 two-component system sensor histidine kinase CreC -
HUW55_RS04835 1038289..1039653 + 1365 WP_016929973.1 cell envelope integrity protein CreD -
HUW55_RS04840 1039691..1040209 - 519 WP_004931683.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16501.62 Da        Isoelectric Point: 11.2159

>T161636 WP_016929976.1 NZ_CP055161:1035673-1036095 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGFGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGMLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLHPPAGNGEEP

Download         Length: 423 bp

>T161636 NZ_CP071236:2040958-2041054 [Serratia marcescens subsp. marcescens ATCC 13880]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT161636 WP_004931679.1 NZ_CP055161:1035426-1035692 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT161636 NZ_CP071236:c2041054-2040914 [Serratia marcescens subsp. marcescens ATCC 13880]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References