Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1834706..1834851 Replicon chromosome
Accession NZ_CP055119
Organism Klebsiella pneumoniae strain SWHIN_100

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1834742..1834844 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1834706..1834851 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ80_RS08935 1829836..1831896 + 2061 WP_004151449.1 oligopeptidase B -
HUZ80_RS08940 1831900..1832559 - 660 WP_021440386.1 exodeoxyribonuclease X -
HUZ80_RS08945 1832638..1832868 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ80_RS08950 1832981..1833355 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ80_RS08955 1833359..1834228 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
HUZ80_RS08960 1834245..1834583 + 339 WP_002911404.1 YebY family protein -
- 1834706..1834851 - 146 - - Antitoxin
- 1834742..1834844 + 103 - - Toxin
HUZ80_RS08965 1835219..1835362 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ80_RS08970 1835467..1836435 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ80_RS08975 1836592..1837245 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HUZ80_RS08980 1837242..1837433 - 192 WP_002911395.1 YebW family protein -
HUZ80_RS08985 1837531..1837770 - 240 WP_002911393.1 YebV family protein -
HUZ80_RS08990 1837886..1839319 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161613 NZ_CP055119:1834742-1834844 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161613 NZ_CP055119:c1834851-1834706 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References