Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1807718..1807863 Replicon chromosome
Accession NZ_CP055106
Organism Klebsiella pneumoniae strain SWHIN_106

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1807754..1807856 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1807718..1807863 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ83_RS08735 1802848..1804908 + 2061 WP_239612436.1 oligopeptidase B -
HUZ83_RS08740 1804912..1805571 - 660 WP_021440386.1 exodeoxyribonuclease X -
HUZ83_RS08745 1805650..1805880 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ83_RS08750 1805993..1806367 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ83_RS08755 1806371..1807240 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
HUZ83_RS08760 1807257..1807595 + 339 WP_002911404.1 YebY family protein -
- 1807718..1807863 - 146 - - Antitoxin
- 1807754..1807856 + 103 - - Toxin
HUZ83_RS08765 1808231..1808374 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ83_RS08770 1808479..1809447 - 969 WP_004151446.1 VirK/YbjX family protein -
HUZ83_RS08775 1809604..1810257 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HUZ83_RS08780 1810254..1810445 - 192 WP_002911395.1 YebW family protein -
HUZ83_RS08785 1810543..1810782 - 240 WP_002911393.1 YebV family protein -
HUZ83_RS08790 1810898..1812331 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T161524 NZ_CP055106:1807754-1807856 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT161524 NZ_CP055106:c1807863-1807718 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References